XP_001262510.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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NCBI Official Full Name
Patatin-like serine hydrolase, putative
NCBI Protein Information
Patatin-like serine hydrolase, putative
UniProt Protein Name
Lysophospholipase nte1
UniProt Synonym Protein Names
Intracellular phospholipase B; Neuropathy target esterase homolog
UniProt Entry Name
NTE1_NEOFI
UniProt Comments for NFIA_030460
Function: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium
By similarity.
Catalytic activity: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
Enzyme regulation: Inhibited by organophosphorus esters
By similarity.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
By similarity.
Sequence similarities: Belongs to the NTE family.Contains 2 cyclic nucleotide-binding domains.Contains 1 patatin domain.
Sequence caution: The sequence EAW20613.1 differs from that shown. Reason: Erroneous initiation.
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Pathways associated with NFIA_030460 recombinant protein
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