NP_003237.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
120,148 Da
NCBI Official Full Name
thrombospondin-1
NCBI Official Synonym Full Names
thrombospondin 1
NCBI Protein Information
thrombospondin-1
UniProt Protein Name
Thrombospondin-1
UniProt Synonym Gene Names
NCBI Summary for THBS1
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]
UniProt Comments for THBS1
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors ().
Research Articles on THBS1
Precautions
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Disclaimer
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Products associated with THBS1 recombinant protein
Pathways associated with THBS1 recombinant protein
Diseases associated with THBS1 recombinant protein
Organs/Tissues associated with THBS1 recombinant protein
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