NP_001034579.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,295 Da
NCBI Official Full Name
CD151 antigen
NCBI Official Synonym Full Names
CD151 molecule (Raph blood group)
NCBI Official Synonym Symbols
GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24 [Similar Products]
NCBI Protein Information
CD151 antigen; CD151 antigen (Raph blood group); hemidesmosomal tetraspanin CD151; membrane glycoprotein SFA-1; platelet surface glycoprotein gp27; platelet-endothelial cell tetraspan antigen 3; platelet-endothelial tetraspan antigen 3; tetraspanin-24; tspan-24
UniProt Protein Name
CD151 antigen
UniProt Synonym Protein Names
GP27; Membrane glycoprotein SFA-1; Platelet-endothelial tetraspan antigen 3; PETA-3; Tetraspanin-24; Tspan-24; CD_antigen: CD151
UniProt Synonym Gene Names
UniProt Entry Name
CD151_HUMAN
NCBI Summary for CD151
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for CD151
CD151: Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD). NPEBD is characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor. Belongs to the tetraspanin (TM4SF) family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: focal adhesion; membrane; integral to plasma membrane; plasma membrane; cytosol
Molecular Function: integrin binding; protein binding
Biological Process: T cell proliferation; cell migration; hemidesmosome assembly; extracellular matrix organization and biogenesis; cell adhesion
Disease: Raph Blood Group System; Nephropathy With Pretibial Epidermolysis Bullosa And Deafness
Research Articles on CD151
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Products associated with anti-CD151 antibody
Pathways associated with anti-CD151 antibody
Diseases associated with anti-CD151 antibody
Organs/Tissues associated with anti-CD151 antibody
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