NP_003785.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35,611 Da
NCBI Official Full Name
sorting nexin-4
NCBI Official Synonym Full Names
sorting nexin 4
NCBI Official Synonym Symbols
NCBI Protein Information
sorting nexin-4
UniProt Protein Name
Sorting nexin-4
UniProt Entry Name
SNX4_HUMAN
NCBI Summary for SNX4
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012]
UniProt Comments for SNX4
SNX4: May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. Belongs to the sorting nexin family.
Chromosomal Location of Human Ortholog: 3q21.2
Cellular Component: SNARE complex; extrinsic to membrane; protein complex; cytoplasmic dynein complex; membrane; early endosome membrane; cytoplasm; plasma membrane
Molecular Function: protein binding; phosphoinositide binding; insulin receptor binding; epidermal growth factor receptor binding
Biological Process: protein transport; vesicle organization and biogenesis; endocytic recycling
Research Articles on SNX4
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Pathways associated with anti-SNX4 antibody
Diseases associated with anti-SNX4 antibody
Organs/Tissues associated with anti-SNX4 antibody
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