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zfGH recombinant protein :: growth hormone Recombinant Protein

Catalog #    MBS400097 zfGH recombinant protein
Unit / Price
0.01 mg  /  $155 +1 FREE 8GB USB
0.05 mg  /  $240 +1 FREE 8GB USB
0.1 mg  /  $330 +1 FREE 8GB USB
0.5 mg  /  $875 +1 FREE 8GB USB
1 mg  /  $1,410 +1 FREE 8GB USB
 
 Go to:     Product Names    Product Info    Accession #s    Product Desc    Diseases/Tissues/Pathways    Applications    References 
 Product Name   

growth hormone (zfGH), Recombinant Protein

 Also Known As   

Zebrafish growth hormone

 Product Synonym Names    Zebrafish growth hormone (zfGH)
 Product Gene Name   

zfGH recombinant protein

[Similar Products]
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 Sequence    The sequence of the first six N-terminal amino acids was determined and was found to be Ala-Gln-Ar g-Leu-Phe- Asn.
 OMIM    139250
 3D Structure    ModBase 3D Structure for P01241
 Host    E Coli
 Purity/Purification    Greater than 99.0% as determined by:
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
(c) Analysis by RP-HPLC.
 Form/Format    White lyophilized (freeze-dried) powder.
 Solubility    It is recommended to reconstitute the lyophilized zfGH in sterile water or 0.4% NaHCO3 adjusted to pH 8-9, not less than 100ug/ml and not more than 3 mg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein.
 Protein Content    Protein quantitation was carried out by UV spectroscopy at 280 nm using the absorbency value of 0.42 as the extinction coefficient for a 0.1% (1mg/ml) solution at pH 8.0 This value is calculated by the DNAman program.
 Dimers and Aggregates    The purified zfGH (21K) consists of > 99% monomers as determined by gel-filtration chromatography.
 Endotoxin    Less than 0.05 ng/ug (IEU/ug) of zfGH (22 K).
 Formulation    The protein was lyophilized from a concentrated (1mg/ml) solution with 0.5% NaHCO3 adjusted to pH 8.
 Biological Activity    zfGH is biologically active in PDF-P1 3B9 cells stably transfected with rabbit GH receptors.
 Preparation and Storage    Lyophilized zfGH although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution at > 0.1 mg/ml and filter sterilization zfGH can be stored at 4 degree C for several weeks. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is recomended. Please prevent freeze-thaw cycles.
 Other Notes for zfGH recombinant protein    Small volumes of zfGH recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
 Searchable Terms for zfGH    anti-zfGH; Buy zfGH recombinant protein, growth hormone Recombinant Protein (MBS400097) product datasheet at MyBioSource, Recombinant Proteins; Growth hormones, prolactins, placental lactogens; 2688; SOMA_HUMAN; zfGH recombinant protein; anti-zfGH.
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Product Description specifically for zfGH recombinant protein

   Recombinant zebrafish growth hormone (zbGH) produced in E.Coli (22 K) is a single, non-glycosylated, polypeptide chain containing 185 amino acids with an additional Ala at its N-terminus and having a molecular mass of 21187 Dalton. zfGH is purified by proprietary chromatographic techniques.
 Product Categories/Family for zfGH recombinant protein    Growth hormones, prolactins, placental lactogens
NCBI/Uniprot data below describe general gene information for zfGH. It may not necessarily be applicable to this product.
 NCBI GI #    183157 [Other Products]
 NCBI GeneID    2688 [Other Products]
 NCBI Accession #    AAA98618.1 [Other Products]
 UniProt Primary Accession #    P01241 [Other Products]
 UniProt Secondary Accession #    Q14405; Q16631; Q5EB53; Q9HBZ1; Q9UMJ7; Q9UNL5; A6NEF6 [Other Products]
 UniProt Related Accession #    P01241 [Other Products]
 Molecular Weight    20,201 Da
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 NCBI Official Full Name    growth hormone
 NCBI Official Synonym Full Names    growth hormone 1
 NCBI Official Symbol    GH1 [Similar Products]
 NCBI Official Synonym Symbols   

GH; GHN; GH-N; hGH-N; IGHD1B

[Similar Products]
 NCBI Protein Information    somatotropin; pituitary growth hormone
 UniProt Protein Name    Somatotropin
 UniProt Synonym Protein Names   

Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone

 UniProt Gene Name    GH1 [Similar Products]
 UniProt Synonym Gene Names    GH; GH-N [Similar Products]
 UniProt Entry Name    SOMA_HUMAN
 NCBI Summary for zfGH    The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]
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 Research Articles on zfGH    1. Analysis of GH1 in a cohort of Brazilian patients revealed that the autosomal recessive form of isolated growth hormone deficiency(IGHD) was more common than the dominant one, and both were found only in severe IGHD.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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Products associated with zfGH recombinant proteinPathways associated with zfGH recombinant protein
 Reference Product  PubMed Publications
 GHR recombinant protein  >21 publications with zfGH and GHR
 STAT5B recombinant protein  >9 publications with zfGH and STAT5B
 IRS1 recombinant protein  >3 publications with zfGH and IRS1
 STAT5A recombinant protein  >3 publications with zfGH and STAT5A
 PRLR recombinant protein  >3 publications with zfGH and PRLR
 JAK2 recombinant protein  >2 publications with zfGH and JAK2
 SOCS2 recombinant protein  >1 publications with zfGH and SOCS2
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Growth Hormone Receptor Signaling Pathway antibodies  Growth Hormone Receptor Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
Diseases associated with zfGH recombinant proteinOrgans/Tissues associated with zfGH recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >71 publications with zfGH and Nervous System Diseases
 Pituitary Neoplasms Antibodies  >42 publications with zfGH and Pituitary Neoplasms
 Growth Disorders Antibodies  >27 publications with zfGH and Growth Disorders
 Breast Neoplasms Antibodies  >11 publications with zfGH and Breast Neoplasms
 Obesity Antibodies  >6 publications with zfGH and Obesity
 Liver Diseases Antibodies  >6 publications with zfGH and Liver Diseases
 Insulin Resistance Antibodies  >6 publications with zfGH and Insulin Resistance
 Cardiovascular Diseases Antibodies  >6 publications with zfGH and Cardiovascular Diseases
 Weight Gain Antibodies  >6 publications with zfGH and Weight Gain
 Isolated Growth Hormone Deficiency, Type II Antibodies  >3 publications with zfGH and Isolated Growth Hormone Deficiency, Type II
 Organ/Tissue Name  Pubmed Publications
 Pituitary Gland Antibodies  >51 publications with zfGH and Pituitary Gland
 Brain Antibodies  >49 publications with zfGH and Brain
 Placenta Antibodies  >7 publications with zfGH and Placenta
 Prostate Antibodies  >2 publications with zfGH and Prostate
 Ear Antibodies  >1 publications with zfGH and Ear
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