NP_006725.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
269,053 Da
NCBI Official Full Name
transcription factor HIVEP2
NCBI Official Synonym Full Names
human immunodeficiency virus type I enhancer binding protein 2
NCBI Official Synonym Symbols
SHN2; ZAS2; MBP-2; MIBP1; ZNF40B; HIV-EP2 [Similar Products]
NCBI Protein Information
transcription factor HIVEP2
UniProt Protein Name
Transcription factor HIVEP2
UniProt Synonym Protein Names
Human immunodeficiency virus type I enhancer-binding protein 2; HIV-EP2; MHC-binding protein 2; MBP-2
UniProt Synonym Gene Names
UniProt Entry Name
ZEP2_HUMAN
NCBI Summary for HIVEP2
This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012]
UniProt Comments for HIVEP2
HIVEP2: This protein specifically binds to the DNA sequence 5'- GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon- beta genes. It may act in T-cell activation.
Protein type: C2H2-type zinc finger protein; DNA-binding
Chromosomal Location of Human Ortholog: 6q23-q24
Cellular Component: nucleoplasm; nucleus
Molecular Function: DNA binding; metal ion binding; sequence-specific DNA binding; transcription factor activity
Biological Process: multicellular organismal development; regulation of transcription, DNA-dependent; signal transduction; transcription from RNA polymerase II promoter
Research Articles on HIVEP2
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Diseases associated with anti-HIVEP2 antibody
Organs/Tissues associated with anti-HIVEP2 antibody
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