MyBioSource
  MyBioSource   MBS462009   LOG IN   MY ACCOUNT   CART CONTENTS   CHECKOUT 
MyBioSource Menu
 ELISA Kit
 Monoclonal Antibody
 Polyclonal Antibody
 Secondary Antibody
 Antigen
 Biochemical
 cDNA Clone
 Peptide
 Rec./Purified Protein

 Antibody Matched Pairs
 Products by Disease
 Products by Pathway

 Advanced Search
 Submit Technical Q&A
 International Distributors
 Contact Us


Our Best Sellers more
 • BETA GALACTOSIDASE, Antibody
 • Programmed cell death protein 6, Recombinant Protein
 • M13 + fd + F1 Filamentous Phages, Antibody
 • Kynurenine, ELISA Kit
 • visfatin, ELISA Kit
 • Multimerin-2 (MMRN2), ELISA Kit
 • KeRatinocyte Growth Factor (KGF), ELISA Kit
 • Solute carrier family 13 member 5 (SLC13A5), ELISA Kit
 • Neurabin-2 (PPP1R9B), ELISA Kit
 • Prostate Stem Cell Antigen (PSCA), Recombinant Protein
  more ...
AMPK-alpha (pT172) antibody :: AMPK-alpha (pT172) [Antibody]
Catalog #    MBS462009
Unit / Price
0.1 mg  /  $375.00 + 1 FREE 8GB USB Flash Drive
    
 Go to:     Product Names    Product Info    Accession #s    Product Desc    Diseases/Tissues/Pathways    Applications    References 
 Product Name    AMPK-alpha (pT172), Antibody
 Also Known As    Rabbit anti Phospho- AMPK alpha 1 (pThr 172)
 Product Synonym Names    Rabbit anti--AMPK alpha 1 (pT172) Phosphospecific; AMPKalpha-1; AMP-activated protein kinase alpha 1;PRKAA1; MGC57364; AMPK
 Product Gene Name    AMPK-alpha (pT172) antibody [Similar Products]
TOP
 Host    Rabbit
 Species Reactivity    Human, Rat, Mouse, Bovine, Canine, Chicken
 Specificity    This antibody recognizes AMPK alpha with a phosphorylated site of Thr 172. It does not cross-react with non-phosphospecific peptide.
 Purity/Purification    The Rabbit IgG is purified by site-modified Epitope Affinity Purification.
 Form/Format    This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
 Concentration    Size: 100 ug/200 ul (lot specific)
 Antigen Preparation    A synthetic peptide surrounding to the epitope -LRTSC- with a phosphorylation site at Thr 172 of AMPK alpha 1 protein from human origin. It is identical among human, mouse, rat, chicken, bovine, dog, and insect species.
 Positive Control    Serum starved HEK293
 Cellular Location    Cytoplasmic
 Preparation and Storage    The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
 Other Notes for AMPK-alpha (pT172) antibody    Small volumes of AMPK-alpha (pT172) antibody may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
TOP
 Product Description specifically for AMPK-alpha (pT172) antibody    AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy balance at both the cellular and the whole body levels. Once activated, it affects a metabolic switch from an anabolic to a catabolic state, both by acutely phosphorylating metabolic enzymes and, in the longer term, by regulating gene expression. AMPK is a heterotrimeric complex composed of a catalytic alpha subunit and regulatory beta and gamma subunits. Binding APM to the beta domains triggers increased phosphorylation at Thr172 on the activation loop of the alpha subunit. AMP Phosphorylation at Thr172 is catalyzed by the tumor suppressor kinase LKB1 or CaMKK-beta, TGF-beta activated kinase-1 (TAK1). AMPKalpha is also phosphorylated at Thr258 and Ser485 (for alpha1; Ser491 for alpha2).
 Applications Tested/Suitable for AMPK-alpha (pT172) antibody    ELISA, Western Blot, Immunohistochemistry
 Application Notes for AMPK-alpha (pT172) antibody    Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
 Testing Data for AMPK-alpha (pT172) antibody    AMPK-alpha (pT172) antibody Testing Data image
TOP
NCBI/Uniprot data below describe general gene information for AMPK-alpha (pT172). It may not necessarily be applicable to this product.
 NCBI GI #    60459958 [Other Products]
 Molecular Weight    63 kDa
TOP
 NCBI Official Full Name    AMPK-alpha subunit
 Product References specifically for AMPK-alpha (pT172) antibody    Jing Chen et al. AMPK regulation of mouse oocyte meiotic resumption in vitro. Developmental Biology, 291 (2), 227-238 (2006).
TOP
 Searchable Name for AMPK-alpha (pT172)    anti-AMPK-alpha (pT172); Buy AMPK-alpha (pT172) antibody :: AMPK-alpha (pT172), Antibody (MBS462009) datasheet at MyBioSource; anti-AMPK-alpha (pT172); AMPK-alpha (pT172); anti-AMPK-alpha (pT172); Rabbit anti Phospho- AMPK alpha 1 (pThr 172); Rabbit anti--AMPK alpha 1 (pT172) Phosphospecific; AMPKalpha-1; AMP-activated protein kinase alpha 1;PRKAA1; MGC57364; AMPK; AMPK-alpha subunit Rabbit anti-Human, Rat, Mouse, Bovine, Canine, Chicken. (Tested application: ELISA, Western Blot, Immunohistochemistry) (NCBI/UniProt 60459958 63 kDa); AMPK-alpha (pT172) antibody; anti-AMPK-alpha (pT172)
 Precautions    This product is for research use only. Not for use in diagnostic or therapeutic procedures.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
TOP
Products related to Rabbit anti Phospho- AMPK alpha 1 (pThr 172)...
 Catalog #  Product Name
 MBS395376  phospho AMPKalpha 1/2 [pT172] (Antibody)
Products associated with AMPK-alpha (pT172) antibodyPathways associated with AMPK-alpha (pT172) antibody
 Product Name  Ref Prod  PubMed Publications
 AMPK-alpha (pT172) antibody  FLNA antibody  >12 publications with AMPK-alpha (pT172) and FLNA
 Product Name  Products by Pathway  Pathway Diagram
 AMPK-alpha (pT172) antibody  Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 AMPK-alpha (pT172) antibody  Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 AMPK-alpha (pT172) antibody  MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 AMPK-alpha (pT172) antibody  MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 AMPK-alpha (pT172) antibody  Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 AMPK-alpha (pT172) antibody  Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Organs/Tissues associated with AMPK-alpha (pT172) antibody
 Organ/Tissue Name  Ref Prod  Pubmed Publications
 Bone Antibodies  AMPK-alpha (pT172) antibody  >13 publications with AMPK-alpha (pT172) and Bone
 Connective Tissue Antibodies  AMPK-alpha (pT172) antibody  >4 publications with AMPK-alpha (pT172) and Connective Tissue
 Heart Antibodies  AMPK-alpha (pT172) antibody  >3 publications with AMPK-alpha (pT172) and Heart
 Muscle Antibodies  AMPK-alpha (pT172) antibody  >3 publications with AMPK-alpha (pT172) and Muscle
 Brain Antibodies  AMPK-alpha (pT172) antibody  >3 publications with AMPK-alpha (pT172) and Brain
 Vascular Antibodies  AMPK-alpha (pT172) antibody  >2 publications with AMPK-alpha (pT172) and Vascular
 Embryonic Tissue Antibodies  AMPK-alpha (pT172) antibody  >2 publications with AMPK-alpha (pT172) and Embryonic Tissue
 Ear Antibodies  AMPK-alpha (pT172) antibody  >1 publications with AMPK-alpha (pT172) and Ear
 Kidney Antibodies  AMPK-alpha (pT172) antibody  >1 publications with AMPK-alpha (pT172) and Kidney
 Umbilical Cord Antibodies  AMPK-alpha (pT172) antibody  >1 publications with AMPK-alpha (pT172) and Umbilical Cord
TOP