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MUC5AC elisa kit :: Human mucin-5AC ELISA Kit

Catalog #    MBS701926 MUC5AC elisa kit
Unit / Price
48 Strip Wells  /  $600 +1 FREE 8GB USB
96 Strip Wells  /  $865 +1 FREE 8GB USB
 Go to:     Product Names    Product Info    Accession #s    Product Desc    Diseases/Tissues/Pathways    Applications    References 
 Product Name   

mucin-5AC (MUC5AC), ELISA Kit

 Also Known As   

Human mucin-5AC, MUC5AC ELISA Kit

 Product Synonym Names    Human mucin-5AC (MUC5AC) ELISA kit; MUC5; gastric mucin; mucin 5; subtypes A and C; tracheobronchial/gastric; mucin 5AC; tracheobronchial mucin; mucin-5AC
 Product Gene Name   

MUC5AC elisa kit

[Similar Products]
 MUC5AC elisa kit Manual   
 Immunogen Sequence Length    5030
 OMIM    158373
 3D Structure    ModBase 3D Structure for P98088
 Species Reactivity    Human
 Specificity    This assay has high sensitivity and excellent specificity for detection of human MUC5AC. No significant cross-reactivity or interference between human MUC5AC and analogues was observed.
 Samples    For the quantitative determination of human mucin-5AC (MUC5AC) concentrations in serum, plasma, cell culture supernates, urine.
 Detection Range    15.6 ng/ml -1000 ng/ml.
 Sensitivity    The minimum detectable dose of human MUC5AC is typically less than 3.9 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 Other Notes for MUC5AC elisa kit    Small volumes of MUC5AC elisa kit may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
 Searchable Terms for MUC5AC    anti-MUC5AC; Buy MUC5AC elisa kit, Human mucin-5AC ELISA Kit (MBS701926) product datasheet at MyBioSource, ELISA Kits; 4586; MUC5A_HUMAN; MUC5AC elisa kit; anti-MUC5AC.

Product Description specifically for MUC5AC elisa kit

   Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for MUC5AC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any MUC5AC present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MUC5AC is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MUC5AC bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI/Uniprot data below describe general gene information for MUC5AC. It may not necessarily be applicable to this product.
 NCBI GI #    160370004 [Other Products]
 NCBI GeneID    4586 [Other Products]
 NCBI Accession #    P98088.3 [Other Products]
 UniProt Primary Accession #    P98088 [Other Products]
 UniProt Secondary Accession #    O60460; O76065; Q13792; Q14425; Q658Q1; Q7M4S5; Q8N4M9; Q8WWQ3; Q8WWQ4; Q8WWQ5 [Other Products]
 UniProt Related Accession #    P98088 [Other Products]
 Molecular Weight    526,608 Da
 NCBI Official Full Name    Mucin-5AC
 NCBI Official Synonym Full Names    mucin 5AC, oligomeric mucus/gel-forming
 NCBI Official Symbol    MUC5AC [Similar Products]
 NCBI Official Synonym Symbols   

TBM; leB; MUC5

[Similar Products]
 NCBI Protein Information    mucin-5AC; mucin 5AC, oligomeric mucus/gel-forming; gastric mucin; tracheobronchial mucin; major airway glycoprotein; lewis B blood group antigen; mucin-5 subtype AC, tracheobronchial; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin 5, subtypes A and C, tracheobronchial/gastric
 UniProt Protein Name    Mucin-5AC
 UniProt Synonym Protein Names   

Gastric mucin; Lewis B blood group antigen; LeB; Major airway glycoprotein; Mucin-5 subtype AC, tracheobronchial; Tracheobronchial mucin; TBM

 UniProt Gene Name    MUC5AC [Similar Products]
 UniProt Synonym Gene Names    MUC5; MUC-5AC; LeB; TBM [Similar Products]
 UniProt Entry Name    MUC5A_HUMAN
 UniProt Comments for MUC5AC    Function: Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.
 UniProt References for MUC5AC    1. "Human mucin gene MUC5AC: organization of its 5'-region and central repetitive region."Escande F., Aubert J.-P., Porchet N., Buisine M.P.Biochem. J. 358:763-772(2001) [PubMed] [Europe PMC] [Abstract]. Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-2448, NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 2449-3797, NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 3798-4169.
2. "Cloning of the amino-terminal and 5'-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts."Li D., Gallup M., Fan N., Szymkowski D.E., Basbaum C.B.J. Biol. Chem. 273:6812-6820(1998) [PubMed] [Europe PMC] [Abstract]. Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1104. Tissue: Trachea.
3. "Cloning and analysis of human gastric mucin cDNA reveals two types of conserved cysteine-rich domains."Klomp L.W., Van Rens L., Strous G.J.Biochem. J. 308:831-838(1995) [PubMed] [Europe PMC] [Abstract]. Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1005-1854.
4. "Proteolytic fragmentation and peptide mapping of human carboxyamidomethylated tracheobronchial mucin."Rose M.C., Kaufman B., Martin B.M.J. Biol. Chem. 264:8193-8199(1989) [PubMed] [Europe PMC] [Abstract]. Cited for: PROTEIN SEQUENCE OF 1752-1773; 1796-1805; 2125-2146; 2169-2178; 2655-2676; 2697-2708; 2953-2974; 2997-3006; 3386-3407; 3428-3439 AND 4012-4033. Tissue: Tracheobronchial mucosa.
5. "Genomic organization of the 3'-region of the human MUC5AC mucin gene: additional evidence for a common ancestral gene for the 11p15.5 mucin gene family."Buisine M.P., Desseyn J.-L., Porchet N., Degand P., Laine A., Aubert J.-P.Biochem. J. 332:729-738(1998) [PubMed] [Europe PMC] [Abstract]. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] OF 3950-5030, VARIANT PRO-4897. Tissue: Placenta and Trachea.
 Research Articles on MUC5AC    1. we report the expression pattern of MUC2, MUC5AC, MUC5B, and MUC6 in a large series of colorectal carcinomas
 Precautions    This product is for research use only. Not for use in diagnostic or therapeutic procedures.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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Products associated with MUC5AC elisa kitPathways associated with MUC5AC elisa kit
 Reference Product  PubMed Publications
 FLNA elisa kit  >12 publications with MUC5AC and FLNA
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 O-linked Glycosylation Of Mucins Pathway antibodies  O-linked Glycosylation Of Mucins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Termination Of O-glycan Biosynthesis Pathway antibodies  Termination Of O-glycan Biosynthesis Pathway Diagram
Organs/Tissues associated with MUC5AC elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with MUC5AC and Bone
 Connective Tissue Antibodies  >4 publications with MUC5AC and Connective Tissue
 Heart Antibodies  >3 publications with MUC5AC and Heart
 Muscle Antibodies  >3 publications with MUC5AC and Muscle
 Brain Antibodies  >3 publications with MUC5AC and Brain
 Vascular Antibodies  >2 publications with MUC5AC and Vascular
 Embryonic Tissue Antibodies  >2 publications with MUC5AC and Embryonic Tissue
 Ear Antibodies  >1 publications with MUC5AC and Ear
 Kidney Antibodies  >1 publications with MUC5AC and Kidney
 Umbilical Cord Antibodies  >1 publications with MUC5AC and Umbilical Cord
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