NP_112457.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,142 Da
NCBI Official Full Name
beta-klotho
NCBI Official Synonym Full Names
klotho beta
NCBI Protein Information
beta-klotho; BKL; klotho beta-like protein
UniProt Protein Name
Beta-klotho
UniProt Synonym Protein Names
Klotho beta-like protein
UniProt Synonym Gene Names
UniProt Entry Name
KLOTB_MOUSE
UniProt Comments for KLB
Klotho beta: Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21. Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.
Protein type: Membrane protein, integral
Cellular Component: membrane; plasma membrane; integral to membrane
Molecular Function: fibroblast growth factor binding; fibroblast growth factor receptor binding; hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process: fibroblast growth factor receptor signaling pathway; positive regulation of cell proliferation; carbohydrate metabolic process
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Pathways associated with KLB elisa kit
Diseases associated with KLB elisa kit
Organs/Tissues associated with KLB elisa kit
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