AAA51766.1
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UniProt Secondary Accession #
Molecular Weight
38,298 Da
NCBI Official Full Name
apolipoprotein H
UniProt Protein Name
Beta-2-glycoprotein 1
UniProt Synonym Protein Names
APC inhibitor; Activated protein C-binding protein; Anticardiolipin cofactor; Apolipoprotein H; Apo-H; Beta-2-glycoprotein I; B2GPI; Beta(2)GPI
UniProt Synonym Gene Names
UniProt Entry Name
APOH_HUMAN
UniProt Comments for ApoH
APOH: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
Protein type: Secreted, signal peptide; Secreted; Lipid-binding
Chromosomal Location of Human Ortholog: 17q24.2
Cellular Component: extracellular matrix; extracellular space; chylomicron; cell surface
Molecular Function: heparin binding; identical protein binding; protein binding; phospholipid binding; glycoprotein binding; lipid binding
Biological Process: negative regulation of angiogenesis; negative regulation of myeloid cell apoptosis; positive regulation of blood coagulation; triacylglycerol metabolic process; negative regulation of fibrinolysis; negative regulation of endothelial cell proliferation; negative regulation of blood coagulation; positive regulation of lipoprotein lipase activity; triacylglycerol transport; blood coagulation, intrinsic pathway; plasminogen activation; regulation of fibrinolysis
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