NP_036456.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,070 Da
NCBI Official Full Name
C-Jun-amino-terminal kinase-interacting protein 2
NCBI Official Synonym Full Names
mitogen-activated protein kinase 8 interacting protein 2
NCBI Protein Information
C-Jun-amino-terminal kinase-interacting protein 2
UniProt Protein Name
C-Jun-amino-terminal kinase-interacting protein 2
UniProt Synonym Protein Names
Islet-brain-2; IB-2; JNK MAP kinase scaffold protein 2; Mitogen-activated protein kinase 8-interacting protein 2
UniProt Synonym Gene Names
NCBI Summary for JIP2
This gene encodes a scaffold protein that is thought to be involved in the regulation of the c-Jun amino-terminal kinase signaling pathway. This protein has been shown to interact with and regulate the activity of MAPK8/JNK1 and MAP2K7/MKK7 kinases. [provided by RefSeq, Jun 2017]
UniProt Comments for JIP2
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins ().
Product References and Citations for anti-JIP2 antibody
Yasuda J., Mol. Cell. Biol. 19:7245-7254(1999). Negri S., Genomics 64:324-330(2000). Dunham I., Nature 402:489-495(1999).
Research Articles on JIP2
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Products associated with anti-JIP2 antibody
Pathways associated with anti-JIP2 antibody
Diseases associated with anti-JIP2 antibody
Organs/Tissues associated with anti-JIP2 antibody
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