NP_689901.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
KH domain-containing, RNA-binding, signal transduction-associated protein 2
NCBI Official Synonym Full Names
KH domain containing, RNA binding, signal transduction associated 2
NCBI Protein Information
KH domain-containing, RNA-binding, signal transduction-associated protein 2
UniProt Protein Name
KH domain-containing, RNA-binding, signal transduction-associated protein 2
UniProt Synonym Protein Names
Sam68-like mammalian protein 1; SLM-1; hSLM-1
UniProt Synonym Gene Names
UniProt Entry Name
KHDR2_HUMAN
UniProt Comments for KHDRBS2
KHDRBS2: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability. Belongs to the KHDRBS family.
Chromosomal Location of Human Ortholog: 6q11.1
Cellular Component: nucleus
Molecular Function: protein binding; protein heterodimerization activity; poly(U) binding; SH2 domain binding; SH3 domain binding; poly(A) binding
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
Product References and Citations for anti-KHDRBS2 antibody
Wang L., et al. Mol. Biol. Rep. 29:369-375(2002). Ota T., et al. Nat. Genet. 36:40-45(2004). Mungall A.J., et al. Nature 425:805-811(2003). Mural R.J., et al. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Cote J., et al. Mol. Biol. Cell 14:274-287(2003).
Research Articles on KHDRBS2
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Products associated with anti-KHDRBS2 antibody
Diseases associated with anti-KHDRBS2 antibody
Organs/Tissues associated with anti-KHDRBS2 antibody
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