NP_001265542.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
protocadherin-1 isoform 3
NCBI Official Synonym Full Names
protocadherin 1
NCBI Official Synonym Symbols
NCBI Protein Information
protocadherin-1
UniProt Protein Name
Protocadherin-1
UniProt Synonym Protein Names
Cadherin-like protein 1; Protocadherin-42; PC42
UniProt Synonym Gene Names
UniProt Entry Name
PCDH1_HUMAN
NCBI Summary for PCDH1
This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for PCDH1
PCDH1: a protocadherin protein within the cadherin superfamily. A membrane protein found at cell-cell boundaries. Involved in neural cell adhesion, suggesting a possible role in neuronal development. Contains an extracelllular region with 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5q31.3
Cellular Component: integral to plasma membrane; plasma membrane; intercellular junction
Molecular Function: calcium ion binding
Biological Process: nervous system development; cell-cell signaling; homophilic cell adhesion
Product References and Citations for anti-PCDH1 antibody
Koppelman, G.H., et al. Am. J. Respir. Crit. Care Med. 180(10):929-935(2009) Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005) Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004) Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004) Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Research Articles on PCDH1
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Products associated with anti-PCDH1 antibody
Diseases associated with anti-PCDH1 antibody
Organs/Tissues associated with anti-PCDH1 antibody
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