NP_003099.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,679 Da
NCBI Official Full Name
transcription factor SOX-11
NCBI Official Synonym Full Names
SRY (sex determining region Y)-box 11
NCBI Official Synonym Symbols
NCBI Protein Information
transcription factor SOX-11
UniProt Protein Name
Transcription factor SOX-11
UniProt Entry Name
SOX11_HUMAN
NCBI Summary for SOX11
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]
UniProt Comments for SOX11
SOX11: Probably important in the developing nervous system. May also have a role in tissue modeling during development.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 2p25
Cellular Component: cytoplasm; nucleus
Molecular Function: translation factor activity, nucleic acid binding; transcription factor activity
Biological Process: neural crest cell development; translation; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of lymphocyte proliferation; glial cell proliferation; neuron differentiation; sympathetic nervous system development; regulation of transforming growth factor beta receptor signaling pathway; embryonic digestive tract morphogenesis; positive regulation of cell proliferation; hard palate development; oligodendrocyte development; kidney development; skeletal development; positive regulation of BMP signaling pathway; glial cell development; positive regulation of neurogenesis; transcription, DNA-dependent; positive regulation of hormone secretion; positive regulation of ossification; embryonic skeletal morphogenesis; positive regulation of osteoblast differentiation; limb bud formation; spinal cord development; positive regulation of transcription from RNA polymerase II promoter; lens morphogenesis in camera-type eye; soft palate development; neural tube formation; positive regulation of neuron differentiation
Disease: Mental Retardation, Autosomal Dominant 27
Research Articles on SOX11
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Products associated with anti-SOX11 antibody
Diseases associated with anti-SOX11 antibody
Organs/Tissues associated with anti-SOX11 antibody
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