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SLC25A6 recombinant protein :: ADP/ATP translocase 3 (SLC25A6) Recombinant Protein

Catalog #    MBS966254 SLC25A6 recombinant protein
Unit / Price
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 Go to:     Product Names    Product Info    Accession #s    Product Desc    Diseases/Tissues/Pathways    Applications    References 
 Product Name   

ADP/ATP translocase 3 (SLC25A6), Recombinant Protein

 Also Known As   

Recombinant Human ADP/ATP translocase 3 (SLC25A6)

 Product Synonym Names    Recombinant ADP/ATP translocase 3 (SLC25A6); ADP/ATP translocase 3; ADP,ATP carrier protein 3 ADP,ATP carrier protein, isoform T2; ANT 2 Adenine nucleotide translocator 3; ANT 3 Solute carrier family 25 member 6
 Product Gene Name   

SLC25A6 recombinant protein

[Similar Products]
 Product Synonym Gene Name    SLC25A6; ANT3; CDABP0051 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
 Sequence Positions    2-298
 Chromosome Location    Chromosome: Y; NC_000024.9 (1455045..1461039, complement). Location: Xp22.32 and Yp11.3
 OMIM    300151
 3D Structure    ModBase 3D Structure for P12236
 Host    E Coli or Yeast
 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal hosts tags may vary (GST-tagged; His-tagged; His-SUMO-tagged). Please inquire to confirm tag information. Additional charge for tag removal.
Tag removal services standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag will remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
 Species    Homo sapiens (Human)
 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes for SLC25A6 recombinant protein    Small volumes of SLC25A6 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SLC25A6 purchase    anti-SLC25A6 cost; Buy SLC25A6 recombinant protein, ADP/ATP translocase 3 (SLC25A6) Recombinant Protein (MBS966254) product datasheet at MyBioSource, Recombinant Proteins; Chromosome: Y; NC_000024.9 (1455045..1461039, complement). Location: Xp22.32 and Yp11.3; 293; ADT3_HUMAN; SLC25A6 recombinant protein price; recombinant protein for SLC25A6
NCBI/Uniprot data below describe general gene information for SLC25A6. It may not necessarily be applicable to this product.
 NCBI GI #    156071462
 NCBI GeneID    293
 NCBI Accession #    NP_001627.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001636.3 [Other Products]
 UniProt Primary Accession #    P12236 [Other Products]
 UniProt Secondary Accession #    Q96C49 [Other Products]
 UniProt Related Accession #    P12236 [Other Products]
 Molecular Weight    32,866 Da [Similar Products]
 NCBI Official Full Name    ADP/ATP translocase 3
 NCBI Official Synonym Full Names    solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
 NCBI Official Symbol    SLC25A6 [Similar Products]
 NCBI Official Synonym Symbols   


[Similar Products]
 NCBI Protein Information    ADP/ATP translocase 3; ANT 2; ANT 3; ADP,ATP carrier protein 3; ADP/ATP translocator of liver; ADP,ATP carrier protein, liver; adenine nucleotide translocator 3; solute carrier family 25 member 6; ADP,ATP carrier protein, isoform T2
 UniProt Protein Name    ADP/ATP translocase 3
 UniProt Synonym Protein Names   

ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ANT 2; Adenine nucleotide translocator 3; ANT 3; Solute carrier family 25 member 6

 UniProt Gene Name    SLC25A6 [Similar Products]
 UniProt Synonym Gene Names    ANT3; ANT 2; ANT 3 [Similar Products]
 UniProt Entry Name    ADT3_HUMAN
 NCBI Summary for SLC25A6    This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2009]
 UniProt Comments for SLC25A6    SLC25A6: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. Belongs to the mitochondrial carrier family.

Protein type: Membrane protein, multi-pass; Transporter, SLC family; Transporter; Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xp22.32 and Yp11.3

Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane; nucleus; mitochondrial inner membrane presequence translocase complex

Molecular Function: protein binding; ATP:ADP antiporter activity

Biological Process: ATP transport; ADP transport; cellular protein metabolic process; viral reproduction; apoptosis; active induction of host immune response by virus; virus-host interaction; energy reserve metabolic process; viral infectious cycle; transmembrane transport; protein targeting to mitochondrion; regulation of insulin secretion
 NCBI References for SLC25A6    1. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation.
2. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs).
3. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
4. Systematic and quantitative assessment of the ubiquitin-modified proteome.
5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 UniProt References for SLC25A6    • DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. Cozens A.L., Runswick M.J., Walker J.E.J. Mol. Biol. 206:261-280(1989) [PubMed: 2541251] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA].
• Pediatric leukemia cDNA sequencing project. Zhou J., Yu W., Tang H., Mei G., Tsang Y.T.M., Bouck J., Gibbs R.A., Margolin J.F.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT PHE-242. Tissue: Leukemia.
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain, Cervix, Eye and Lung. [4]Bienvenut W.V.Submitted (JUL-2004) to UniProtKBCited for: PROTEIN SEQUENCE OF 2-10, ACETYLATION AT THR-2, MASS SPECTROMETRY. Tissue: B-cell lymphoma.
• Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver. Houldsworth J., Attardi G.Proc. Natl. Acad. Sci. U.S.A. 85:377-381(1988) [PubMed: 2829183] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 36-298. Tissue: Liver.
 Research Articles on SLC25A6    1. The dynamics of the molecular interactions between the C-terminal region of PB1-F2 protein and VDAC1 and ANT3 were expounded by employing an in silico approach.
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >3 publications with SLC25A6 and Muscle
 Liver Antibodies  >2 publications with SLC25A6 and Liver
 Embryonic Tissue Antibodies  >2 publications with SLC25A6 and Embryonic Tissue
 Adipose Tissue Antibodies  >1 publications with SLC25A6 and Adipose Tissue
 Pituitary Gland Antibodies  >1 publications with SLC25A6 and Pituitary Gland
 Connective Tissue Antibodies  >1 publications with SLC25A6 and Connective Tissue
 Heart Antibodies  >1 publications with SLC25A6 and Heart
 Kidney Antibodies  >1 publications with SLC25A6 and Kidney
 Testis Antibodies  >1 publications with SLC25A6 and Testis
 Skin Antibodies  >1 publications with SLC25A6 and Skin
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