NP_000015.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,459 Da
NCBI Official Full Name
beta-2 adrenergic receptor
NCBI Official Synonym Full Names
adrenoceptor beta 2
NCBI Official Synonym Symbols
BAR; B2AR; ADRBR; ADRB2R; BETA2AR [Similar Products]
NCBI Protein Information
beta-2 adrenergic receptor
UniProt Protein Name
Beta-2 adrenergic receptor
UniProt Synonym Protein Names
Beta-2 adrenoreceptor; Beta-2 adrenoceptor
UniProt Synonym Gene Names
NCBI Summary for ADRB2
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
UniProt Comments for ADRB2
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Product References and Citations for anti-ADRB2 antibody
Schofield P.R., Nucleic Acids Res. 15:3636-3636(1987). Kobilka B.K., Proc. Natl. Acad. Sci. U.S.A. 84:46-50(1987). Chung F.-Z., FEBS Lett. 211:200-206(1987).
Research Articles on ADRB2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-ADRB2 antibody
Pathways associated with anti-ADRB2 antibody
Diseases associated with anti-ADRB2 antibody
Organs/Tissues associated with anti-ADRB2 antibody
|