NP_110389.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,498 Da
NCBI Official Full Name
class E basic helix-loop-helix protein 41
NCBI Official Synonym Full Names
basic helix-loop-helix family, member e41
NCBI Protein Information
class E basic helix-loop-helix protein 41; enhancer-of-split and hairy-related protein 1; differentially expressed in chondrocytes protein 2; basic helix-loop-helix domain containing, class B, 3
UniProt Protein Name
Class E basic helix-loop-helix protein 41
UniProt Synonym Protein Names
Class B basic helix-loop-helix protein 3; bHLHb3; Differentially expressed in chondrocytes protein 2; hDEC2; Enhancer-of-split and hairy-related protein 1
UniProt Synonym Gene Names
UniProt Entry Name
BHE41_HUMAN
NCBI Summary for BHLHB3
This gene encodes a transcription factor that belongs to the Hairy/Enhancer of Split subfamily of basic helix-loop-helix factors. The encoded protein functions as a transcriptional repressor and as a regulator of molecular clock. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, May 2010]
UniProt Comments for BHLHB3
BHLHB3: May be a transcriptional repressor that represses both basal and activated transcription. Homodimerize.
Chromosomal Location of Human Ortholog: 12p12.1
Cellular Component: nucleus
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; MRF binding; protein binding; protein homodimerization activity; protein heterodimerization activity; histone deacetylase binding; bHLH transcription factor binding; transcription corepressor activity
Biological Process: circadian rhythm; transcription from RNA polymerase II promoter; cell proliferation; organ morphogenesis; negative regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; negative regulation of transcription, DNA-dependent; cell differentiation
Disease: Short Sleeper
Research Articles on BHLHB3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-BHLHB3 antibody
Pathways associated with anti-BHLHB3 antibody
Diseases associated with anti-BHLHB3 antibody
Organs/Tissues associated with anti-BHLHB3 antibody
|