NP_005915.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,594 Da
NCBI Official Full Name
homeobox protein MOX-2
NCBI Official Synonym Full Names
mesenchyme homeobox 2
NCBI Official Synonym Symbols
NCBI Protein Information
homeobox protein MOX-2
UniProt Protein Name
Homeobox protein MOX-2
UniProt Synonym Protein Names
Growth arrest-specific homeobox; Mesenchyme homeobox 2
UniProt Synonym Gene Names
NCBI Summary for MEOX2
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008]
UniProt Comments for MEOX2
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
Product References and Citations for anti-MEOX2 antibody
Grigoriou M., Genomics 26:550-555(1995). Lepage D.F., Genomics 24:535-540(1994). Hillier L.W., Nature 424:157-164(2003).
Research Articles on MEOX2
Precautions
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Products associated with anti-MEOX2 antibody
Diseases associated with anti-MEOX2 antibody
Organs/Tissues associated with anti-MEOX2 antibody
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