View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Mouse 4-Amino Biphenyl DNA Monoclonal Antibody Catalog # MBS600356 Unit / Price 0.1 mL / $735 +1 FREE 8GB USB 5x0.1 mL / $3,125 +3 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name 4-Amino Biphenyl DNA, Monoclonal Antibody Full Product Name 4-Amino Biphenyl DNA (4-AMBP DNA, 4-Aminobiphenyl DNA) Product Synonym Names Anti -4-Amino Biphenyl DNA (4-AMBP DNA, 4-Aminobiphenyl DNA) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Clone Number 8J250 Host Mouse Specificity This antibody is specific for 4-amino Biphenyl DNA. Crossreactivity: All DNAs Purity/Purification Affinity PurifiedPurified by Protein G affinity chromatography. Form/Format Supplied as a liquid (ascites). Immunogen 4-amino Biphenyl DNA. Cellular Localization Nuclear Preparation and Storage May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Other Notes Small volumes of anti-4-Amino Biphenyl DNA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-4-Amino Biphenyl DNA antibody 4-amino Biphenyl (4-ABP) is an aromatic amine (arylamine). 4-ABP can be found as a constituent of tobacco smoke, in the form of an environmental carcinogen. It is metabolized by hepatic cytochrome P4501A2 to yield a direct-acting mutagen known as N-hydroxy-aminobiphenyl. Yet, the accumulation of biologically active metabolites is dependent on the activation and detoxification of N-acetylation. 4-ABP has been shown to be a bladder carcinogen in humans and rodents. As well as genetic factors, 4-ABP may also play a role in breast cancer. It is hypothesized that smokers may have higher levels of DNA adducts than non-smokers and that the role of 4-ABP-DNA adducts and their relationship to tobacco exposure may be related to breast tumorigenesis. The antibody has been used to investigate the role of 4-ABP in the study of human breast cancer by measuring 4-ABP-DNA adducts. Product Categories/Family for anti-4-Amino Biphenyl DNA antibody Antibodies; Abs to Transcription Factors Applications Tested/Suitable for anti-4-Amino Biphenyl DNA antibody ELISA (EL/EIA), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) Application Notes for anti-4-Amino Biphenyl DNA antibody Suitable for use in Immunofluorescence, ELISA, Immunohistochemistry and Immunocytochemistry.Dilution: ELISA: 1:50-1:100Immunohistochemistry: 1:50-1:100Immunocytochemistry: 1:50-1:100Immunofluorescence: 1:50-1:100 TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP