NP_065109
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,875 Da
NCBI Official Full Name
patatin-like phospholipase domain-containing protein 2
NCBI Official Synonym Full Names
patatin like phospholipase domain containing 2
NCBI Official Synonym Symbols
ATGL; TTS2; PEDF-R; FP17548; TTS-2.2; iPLA2zeta; 1110001C14Rik [Similar Products]
NCBI Protein Information
patatin-like phospholipase domain-containing protein 2
UniProt Protein Name
Patatin-like phospholipase domain-containing protein 2
UniProt Synonym Protein Names
Adipose triglyceride lipase; Calcium-independent phospholipase A2; Desnutrin; IPLA2-zeta; Pigment epithelium-derived factor; TTS2.2; Transport-secretion protein 2; TTS2
UniProt Synonym Gene Names
NCBI Summary for ATGL
This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy. [provided by RefSeq, Jul 2010]
UniProt Comments for ATGL
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes (PubMed:16239926). May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
Product References and Citations for anti-ATGL antibody
Fischer J, et al., (2007) Nat Genet 39 (1):28-30; Elena S, et al., (2006) EMBO Rep 7 (1):106-113; Zimmermann R, et al., (2004) Science 306 (5700):1383-1386
Research Articles on ATGL
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Products associated with anti-ATGL antibody
Pathways associated with anti-ATGL antibody
Diseases associated with anti-ATGL antibody
Organs/Tissues associated with anti-ATGL antibody
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