View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-ADRBK1 antibody :: Adrenergic Receptor Kinase, beta 1 Monoclonal Antibody Catalog # MBS604719 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Adrenergic Receptor Kinase, beta 1 (ADRBK1), Monoclonal Antibody Full Product Name Adrenergic Receptor Kinase, beta 1 (bARK1, B1 AR, ARK1 beta, G Protein Coupled Receptor Kinase 2, GPCR K2, GRK2) Product Synonym Names Anti -Adrenergic Receptor Kinase, beta 1 (bARK1, B1 AR, ARK1 beta, G Protein Coupled Receptor Kinase 2, GPCR K2, GRK2) Product Gene Name anti-ADRBK1 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Chromosome Location Chromosome: 11; NC_000011.9 (67033905..67054029). Location: 11q13.1 OMIM 109635 3D Structure ModBase 3D Structure for P25098 Clonality Monoclonal Isotype IgG Clone Number 6k13 Host Host: Rabbit; Source: Human Species Reactivity Human, Mouse, Rat Specificity Recognizes human B-ARK1 Purity/Purification SupernatantSupernatant Form/Format Supplied as a liquid Immunogen A synthetic peptide corresponding to residues in the C-terminus of human B-ARK1 Preparation and Storage May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Other Notes Small volumes of anti-ADRBK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-ADRBK1 antibody Adrenergic receptor kinase (beta-ARK1) also known as GRK2 is part of the G Serine /Threonine protein-coupled receptor kinase family (1). B-ARK1 specifically phosphorylates G protein-coupled receptors in their activated form (agonist-bound state). Phosphorylation occurs in the carboxyl terminal tail of the receptor(2). Additionally, phosphorylation of the receptor by B-ARK1 requires beta-Arrestin to induce complete homologous desentisization(3). Product Categories/Family for anti-ADRBK1 antibody Antibodies; Abs to G Protein Receptors Applications Tested/Suitable for anti-ADRBK1 antibody Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) Application Notes for anti-ADRBK1 antibody Suitable for use in Flow Cytometry, Western Blotting, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.Dilution: Flow Cytometry: 1:100Western Blotting: 1:500Immunohistochemistry: 1:100-250Immunocytochemistry: 1:100-250Immunoprecipitation: 1:80 TOP NCBI/Uniprot data below describe general gene information for ADRBK1. It may not necessarily be applicable to this product. NCBI GI # 23272739 NCBI GeneID 156 UniProt Primary Accession # P25098 [Other Products] UniProt Secondary Accession # Q13837; Q6GTT3; B0ZBE1[Other Products] UniProt Related Accession # P25098; Q59F73[Other Products] Molecular Weight 79,574 Da[Similar Products] TOP NCBI Official Full Name Adrenergic, beta, receptor kinase 1 NCBI Official Synonym Full Names adrenergic, beta, receptor kinase 1 NCBI Official Symbol ADRBK1 [Similar Products] NCBI Official Synonym Symbols GRK2; BARK1; FLJ16718; BETA-ARK1 [Similar Products] NCBI Protein Information beta-adrenergic receptor kinase 1; beta-ARK-1; OTTHUMP00000235171; G-protein coupled receptor kinase 2 UniProt Protein Name Beta-adrenergic receptor kinase 1 UniProt Synonym Protein Names G-protein coupled receptor kinase 2 UniProt Gene Name ADRBK1 [Similar Products] UniProt Synonym Gene Names BARK; BARK1; GRK2 [Similar Products] UniProt Entry Name ARBK1_HUMAN TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-ADRBK1 antibody Reference Product PubMed Publications SRC antibody >24 publications with ADRBK1 and SRC ADRA2A antibody >17 publications with ADRBK1 and ADRA2A MAPK3 antibody >16 publications with ADRBK1 and MAPK3 EGF antibody >10 publications with ADRBK1 and EGF EGFR antibody >7 publications with ADRBK1 and EGFR RHO antibody >7 publications with ADRBK1 and RHO GIT1 antibody >5 publications with ADRBK1 and GIT1 PEBP1 antibody >5 publications with ADRBK1 and PEBP1 PRKCA antibody >4 publications with ADRBK1 and PRKCA CCR4 antibody >2 publications with ADRBK1 and CCR4 Pathways associated with anti-ADRBK1 antibody Products by Pathway Pathway Diagram CXCR4-mediated Signaling Events Pathway antibodies CXCR4-mediated Signaling Events Pathway Diagram Ca-dependent Events Pathway antibodies Ca-dependent Events Pathway Diagram CaM Pathway antibodies CaM Pathway Diagram Calmodulin Induced Events Pathway antibodies Calmodulin Induced Events Pathway Diagram Chemokine Signaling Pathway antibodies Chemokine Signaling Pathway Diagram Chemokine Signaling Pathway antibodies Chemokine Signaling Pathway Diagram Endocytosis Pathway antibodies Endocytosis Pathway Diagram Endocytosis Pathway antibodies Endocytosis Pathway Diagram G Alpha (q) Signalling Events Pathway antibodies G Alpha (q) Signalling Events Pathway Diagram G-protein Mediated Events Pathway antibodies G-protein Mediated Events Pathway Diagram Diseases associated with anti-ADRBK1 antibody Disease Name Pubmed Publications Hypertension Antibodies >31 publications with ADRBK1 and Hypertension Inflammation Antibodies >27 publications with ADRBK1 and Inflammation Neoplasms Antibodies >21 publications with ADRBK1 and Neoplasms Hypertrophy Antibodies >17 publications with ADRBK1 and Hypertrophy Pain Antibodies >15 publications with ADRBK1 and Pain Neurodegenerative Diseases Antibodies >10 publications with ADRBK1 and Neurodegenerative Diseases Cardiomegaly Antibodies >10 publications with ADRBK1 and Cardiomegaly Necrosis Antibodies >10 publications with ADRBK1 and Necrosis Genital Diseases, Male Antibodies >7 publications with ADRBK1 and Genital Diseases, Male Hyperalgesia Antibodies >7 publications with ADRBK1 and Hyperalgesia Organs/Tissues associated with anti-ADRBK1 antibody Organ/Tissue Name Pubmed Publications Muscle Antibodies >83 publications with ADRBK1 and Muscle Blood Antibodies >72 publications with ADRBK1 and Blood Brain Antibodies >69 publications with ADRBK1 and Brain Kidney Antibodies >53 publications with ADRBK1 and Kidney Vascular Antibodies >35 publications with ADRBK1 and Vascular Nerve Antibodies >17 publications with ADRBK1 and Nerve Ovary Antibodies >10 publications with ADRBK1 and Ovary Lung Antibodies >9 publications with ADRBK1 and Lung Eye Antibodies >9 publications with ADRBK1 and Eye Bone Antibodies >8 publications with ADRBK1 and Bone TOP © 2006-24 MyBioSource.com. 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