Q95122
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CD14
NCBI Protein Information
monocyte differentiation antigen CD14; CD14 antigen; myeloid cell-specific leucine-rich glycoprotein
UniProt Protein Name
Monocyte differentiation antigen CD14
UniProt Synonym Protein Names
Myeloid cell-specific leucine-rich glycoprotein
UniProt Entry Name
CD14_BOVIN
UniProt Comments for CD14
Function: Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules
Subunit structure: Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4
Subcellular location: Cell membrane; Lipid-anchor › GPI-anchor
Sequence similarities: Contains 11 LRR (leucine-rich) repeats.
Research Articles on CD14
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Pathways associated with anti-CD14 antibody
Diseases associated with anti-CD14 antibody
Organs/Tissues associated with anti-CD14 antibody
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