View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List Mouse Cav beta 4Ca +2 Channel Monoclonal Antibody Catalog # MBS190594 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Cav beta 4Ca +2 Channel, Monoclonal Antibody Full Product Name Anti-Cav beta 4 Ca+2 Channel Monoclonal Antibody Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Immunogen Sequence Positions 458-474 Clonality Monoclonal Isotype lgG1 Clone Number S10-7 Host Mouse Species Reactivity Human, mouse, rat Specificity Cav beta 4Ca +2 ChannelThis antibody recognizes human, mouse, and rat Cav54. It does not cross-react with +!) 51b, Cav52a, or Cav53. Form/Format 100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography. Antigen Synthetic peptide corresponding to aa 458-474 of rat Cav54. Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system. Preparation and Storage This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing. Other Notes Small volumes of anti-Cav beta 4Ca +2 Channel antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-Cav beta 4Ca +2 Channel antibody Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Calcium channel, voltage-dependent, beta 4 subunit, also known as CACNB4, belongs to the calcium channel beta subunit family. This protein plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting, and shifting the voltage dependence of activation and inactivation. Mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Alternate transcriptional splice variants of this gene, encoding different isoforms, have been identified. Applications Tested/Suitable for anti-Cav beta 4Ca +2 Channel antibody Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence Application Notes for anti-Cav beta 4Ca +2 Channel antibody Immunoblotting: use at 1ug/ml. A band of ~50kDa is detected. Immunohistochemistry and Immunocytochemistry. use at 0.1-1 ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Rat brain lysate TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP