NP_057306.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
69,838 Da
NCBI Official Full Name
Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (DDX41), mRNA
NCBI Official Synonym Full Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
NCBI Official Synonym Symbols
NCBI Protein Information
probable ATP-dependent RNA helicase DDX41; 2900024F02Rik; DEAD box protein 41; DEAD box protein abstrakt homolog; DEAD-box protein abstrakt; putative RNA helicase
UniProt Protein Name
Probable ATP-dependent RNA helicase DDX41
UniProt Synonym Protein Names
DEAD box protein 41; DEAD box protein abstrakt homolog
UniProt Entry Name
DDX41_HUMAN
NCBI Summary for DDX41
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression. [provided by RefSeq, Jul 2008]
UniProt Comments for DDX41
DDX41: Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing. Belongs to the DEAD box helicase family. DDX41 subfamily.
Protein type: RNA splicing; EC 3.6.4.13; Helicase; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 5q35.3
Cellular Component: membrane; endoplasmic reticulum; cytosol
Molecular Function: protein binding; DNA binding; zinc ion binding; helicase activity; ATP binding
Biological Process: RNA processing; nuclear mRNA splicing, via spliceosome; regulation of interferon type I production; apoptosis; multicellular organismal development; positive regulation of interferon type I production; innate immune response; positive regulation of transcription from RNA polymerase II promoter; defense response to virus
Research Articles on DDX41
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Pathways associated with anti-DDX41 antibody
Diseases associated with anti-DDX41 antibody
Organs/Tissues associated with anti-DDX41 antibody
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