NP_001512.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
64,003 Da
NCBI Official Full Name
Homo sapiens general transcription factor IIIC, polypeptide 2, beta 110kDa (GTF3C2), transcript variant 1, mRNA
NCBI Official Synonym Full Names
general transcription factor IIIC, polypeptide 2, beta 110kDa
NCBI Protein Information
general transcription factor 3C polypeptide 2; TF3C-beta; TFIIIC 110 kDa subunit; transcription factor IIIC 110 kDa subunit; transcription factor IIIC subunit beta
UniProt Protein Name
General transcription factor 3C polypeptide 2
UniProt Synonym Protein Names
TF3C-beta; Transcription factor IIIC 110 kDa subunit; TFIIIC 110 kDa subunit; TFIIIC110; Transcription factor IIIC subunit beta
UniProt Entry Name
TF3C2_HUMAN
UniProt Comments for GTF3C2
GTF3C2: Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription initiation complex
Chromosomal Location of Human Ortholog: 2p23.3
Cellular Component: nucleoplasm; transcription factor TFIIIC complex
Molecular Function: DNA binding
Biological Process: transcription from RNA polymerase III promoter; transcription, DNA-dependent; 5S class rRNA transcription; gene expression; tRNA transcription from RNA polymerase III promoter
Research Articles on GTF3C2
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Pathways associated with anti-GTF3C2 antibody
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