View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-MVP antibody :: Rat anti-Human LRP, MVP Monoclonal Antibody Catalog # MBS600705 Unit / Price 0.025 mg / $625 +1 FREE 8GB USB 5x0.025 mg / $2,645 +3 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name LRP, MVP, Monoclonal Antibody Full Product Name LRP, MVP (Major Vault Protein, Lung-resistance Related Protein) Product Synonym Names Anti -LRP, MVP (Major Vault Protein, Lung-resistance Related Protein) Product Gene Name anti-MVP antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 605088 3D Structure ModBase 3D Structure for Q14764 Clonality Monoclonal Isotype IgG2a Clone Number 6D536 Host Rat Species Reactivity Human Specificity SpRecognizes an internal epitope of human MVP/LRP, which is strongly overexpressed in various human non-P-glycoprotein MDR tumor cell lines. Purity/Purification SupernatantSupernatant Form/Format Liquid. Antibody in serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide. Immunogen Human MVP/LRP (major vault protein/lung resistance protein). Preparation and Storage -20 degree C Other Notes Small volumes of anti-MVP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Product Categories/Family for anti-MVP antibody Antibodies; Abs to Multi Drug Resistance (MDR) Applications Tested/Suitable for anti-MVP antibody Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) Application Notes for anti-MVP antibody Flow Cytometry (cell permeabilization required), Immunocytochemistry (cytospin preparations), Immunohistochemistry (frozen sections, paraffin sections), Recommended starting dilution is 1:20. Optimal conditions must be determined individually for each application. TOP NCBI/Uniprot data below describe general gene information for MVP. It may not necessarily be applicable to this product. NCBI GI # 19577290 NCBI Accession # CAA56256.2 [Other Products] UniProt Primary Accession # Q14764 [Other Products] UniProt Secondary Accession # Q96BG4; Q9BPW6; Q9BQT1; Q9UBD1[Other Products] Molecular Weight 99,327 Da[Similar Products] TOP NCBI Official Full Name lrp UniProt Protein Name Major vault protein UniProt Synonym Protein Names Lung resistance-related protein Protein Family Hyperpolarization-activated voltage-gated potassium channel UniProt Gene Name MVP [Similar Products] UniProt Synonym Gene Names LRP; MVP [Similar Products] UniProt Entry Name MVP_HUMAN TOP TOP UniProt Comments for MVP MVP: Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.Protein type: RNA-bindingChromosomal Location of Human Ortholog: 16p11.2Cellular Component: cytoskeleton; membrane; perinuclear region of cytoplasm; cytoplasm; nuclear pore; nucleus; ribonucleoprotein complexMolecular Function: protein binding; protein kinase binding; protein phosphatase bindingBiological Process: cell proliferation; protein transport; mRNA transport; negative regulation of protein amino acid autophosphorylation Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-MVP antibody Reference Product PubMed Publications ABCB1 antibody >40 publications with MVP and ABCB1 ABCC1 antibody >7 publications with MVP and ABCC1 PTEN antibody >5 publications with MVP and PTEN ABCC3 antibody >4 publications with MVP and ABCC3 STAT1 antibody >2 publications with MVP and STAT1 PTPN11 antibody >1 publications with MVP and PTPN11 YPEL4 antibody >1 publications with MVP and YPEL4 Diseases associated with anti-MVP antibody Disease Name Pubmed Publications Heart Diseases Antibodies >736 publications with MVP and Heart Diseases Neoplasms Antibodies >283 publications with MVP and Neoplasms Brain Diseases Antibodies >75 publications with MVP and Brain Diseases Neoplasm Metastasis Antibodies >32 publications with MVP and Neoplasm Metastasis Fibrosis Antibodies >30 publications with MVP and Fibrosis Hypertension Antibodies >29 publications with MVP and Hypertension Hypertrophy Antibodies >29 publications with MVP and Hypertrophy Disease Models, Animal Antibodies >29 publications with MVP and Disease Models, Animal Myocardial Infarction Antibodies >26 publications with MVP and Myocardial Infarction Neurobehavioral Manifestations Antibodies >23 publications with MVP and Neurobehavioral Manifestations Organs/Tissues associated with anti-MVP antibody Organ/Tissue Name Pubmed Publications Heart Antibodies >524 publications with MVP and Heart Blood Antibodies >253 publications with MVP and Blood Lung Antibodies >208 publications with MVP and Lung Vascular Antibodies >97 publications with MVP and Vascular Brain Antibodies >77 publications with MVP and Brain Muscle Antibodies >62 publications with MVP and Muscle Bone Antibodies >56 publications with MVP and Bone Connective Tissue Antibodies >43 publications with MVP and Connective Tissue Liver Antibodies >32 publications with MVP and Liver Bladder Antibodies >29 publications with MVP and Bladder TOP © 2006-24 MyBioSource.com. 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