View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List Mouse Tacrolimus (FK-506) Monoclonal Antibody Catalog # MBS312299 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Tacrolimus (FK-506), Monoclonal Antibody Popular Item Full Product Name MAb to FK-506 Product Synonym Names Monoclonal Antibody to Tacrolimus (FK-506) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgM Clone Number B246M Host Mouse Specificity Tacrolimus (FK-506)Detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplatation to reduce organ rejection. Purity/Purification Euglobulin precipitation and dialysis Form/Format Purified, Liquid; Tris buffered saline, pH 8.0 Concentration 1mg/ml (lot specific) Source Culture Immunogen FK-506 BSA conjugate Preservative 0.09% Sodium azide Important Note Centrifuge before opening to ensure complete recovery of vial contents. Preparation and Storage Short term store at 2 to 8°C. Long term aliquot and store at -20°C. Prepare working dilution only prior to immediate use. Avoid multiple freeze/thaw cycles. ISO Certification Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory. Other Notes Small volumes of anti-Tacrolimus (FK-506) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Product Categories/Family for anti-Tacrolimus (FK-506) antibody Monoclonal Antibodies to Drugs Applications Tested/Suitable for anti-Tacrolimus (FK-506) antibody ELISA (EIA) Application Notes for anti-Tacrolimus (FK-506) antibody Each laboratory should determine an optimum working titer for use in its particular application.Other applications have not been tested but use in such assays should not necessarily be excluded. TOP Product References and Citations for anti-Tacrolimus (FK-506) antibody • Letko, E., et al., (1999), "Tacrolimus (FK506)", Ann. Allergy Asthma Immunol., 83: 179-189 TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP