View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-TFRC antibody :: Transferrin Receptor Monoclonal Antibody Catalog # MBS660240 Unit / Price 1 mg / $630 +1 FREE 8GB USB 5 mg / $2,370 +2 FREE 8GB USB 10 mg / $4,375 +5 FREE 8GB USB 15 mg / $6,160 +7 FREE 8GB USB 25 mg / $9,665 +10 FREE 8GB USB 50 mg / $17,845 +10 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Transferrin Receptor (TFRC), Monoclonal Antibody Popular Item Full Product Name Monoclonal mouse anti-human soluble transferrin receptor Product Gene Name anti-TFRC antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 190010 Clonality Monoclonal Isotype IgG2b Clone Number 23D10 Specificity Human soluble transferrin receptor and complex between soluble transferrin receptor and transferrin . Purity/Purification >92%; Protein A chromatography Form/Format PBS, pH 7.4, 0.09 % sodium azide (NaN3) Concentration 5.9 mg/mL (lot specific) Immunogen Purified human soluble transferrin receptor Appearance Clear or slightly opalescent solution Concentration Note Determined by Spectrophotometry at A280 using extinction coefficient 1.4 Purity Examined By Gel electrophoresis and gel scanning Preparation and Storage +4°C (+2..+8°C allowed). Other Notes Small volumes of anti-TFRC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-TFRC antibody Mouse monoclonal antibody produced in ascites. Hybridoma clone derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice. NCBI/Uniprot data below describe general gene information for TFRC. It may not necessarily be applicable to this product. NCBI GI # 339516 NCBI GeneID 7037 NCBI Accession # AAA61153.1 [Other Products] UniProt Secondary Accession # Q1HE24; Q59G55; Q9UCN0; Q9UCU5; Q9UDF9; Q9UK21; D3DXB0[Other Products] UniProt Related Accession # P02786[Other Products] TOP NCBI Official Full Name transferrin receptor NCBI Official Synonym Full Names transferrin receptor NCBI Official Symbol TFRC [Similar Products] NCBI Official Synonym Symbols T9; TR; TFR; p90; CD71; TFR1; TRFR [Similar Products] NCBI Protein Information transferrin receptor protein 1; transferrin receptor (p90, CD71) UniProt Protein Name Transferrin receptor protein 1 UniProt Synonym Protein Names T9; p90; CD_antigen: CD71Transferrin receptor protein 1, serum form; sTfR Protein Family Transferrin receptor protein UniProt Gene Name TFRC [Similar Products] UniProt Synonym Gene Names TR; TfR; TfR1; Trfr; sTfR [Similar Products] UniProt Entry Name TFR1_HUMAN TOP TOP UniProt Comments for TFRC TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.Protein type: Cell surface; Membrane protein, integral; Receptor, misc.Chromosomal Location of Human Ortholog: 3q29Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; integral to plasma membrane; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; membrane; perinuclear region of cytoplasm; plasma membrane; melanosome; vesicle; endosome; external side of plasma membraneMolecular Function: identical protein binding; protein binding; transferrin receptor activity; double-stranded RNA bindingBiological Process: receptor-mediated endocytosis; viral reproduction; cellular iron ion homeostasis; transferrin transport; positive regulation of bone resorption; osteoclast differentiation; regulation of cell growth; transmembrane transport; regulation of cell proliferation Product References and Citations for anti-TFRC antibody See all Soluble Transferrin Receptor Refrences Research Articles on TFRC 1. these findings suggest that TFR1 has an important role in sphingosine kinase 1-mediated oncogenesis. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. 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TOP Products associated with anti-TFRC antibody Reference Product PubMed Publications HFE antibody >21 publications with TFRC and HFE MYC antibody >14 publications with TFRC and MYC B2M antibody >12 publications with TFRC and B2M EPO antibody >4 publications with TFRC and EPO FTH1 antibody >3 publications with TFRC and FTH1 STEAP3 antibody >1 publications with TFRC and STEAP3 Pathways associated with anti-TFRC antibody Products by Pathway Pathway Diagram Clathrin Derived Vesicle Budding Pathway antibodies Clathrin Derived Vesicle Budding Pathway Diagram Endocytosis Pathway antibodies Endocytosis Pathway Diagram Endocytosis Pathway antibodies Endocytosis Pathway Diagram FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram Golgi Associated Vesicle Biogenesis Pathway antibodies Golgi Associated Vesicle Biogenesis Pathway Diagram HIF-1 Signaling Pathway antibodies HIF-1 Signaling Pathway Diagram HIF-1-alpha Transcription Factor Network Pathway antibodies HIF-1-alpha Transcription Factor Network Pathway Diagram Hematopoietic Cell Lineage Pathway antibodies Hematopoietic Cell Lineage Pathway Diagram Hematopoietic Cell Lineage Pathway antibodies Hematopoietic Cell Lineage Pathway Diagram Iron Metabolism In Placenta Pathway antibodies Iron Metabolism In Placenta Pathway Diagram Diseases associated with anti-TFRC antibody Disease Name Pubmed Publications Iron Metabolism Disorders Antibodies >29 publications with TFRC and Iron Metabolism Disorders Anemia Antibodies >21 publications with TFRC and Anemia Disease Models, Animal Antibodies >15 publications with TFRC and Disease Models, Animal Anemia, Iron-Deficiency Antibodies >11 publications with TFRC and Anemia, Iron-Deficiency Brain Diseases Antibodies >10 publications with TFRC and Brain Diseases Inflammation Antibodies >9 publications with TFRC and Inflammation Liver Diseases Antibodies >8 publications with TFRC and Liver Diseases Lung Neoplasms Antibodies >8 publications with TFRC and Lung Neoplasms Breast Neoplasms Antibodies >6 publications with TFRC and Breast Neoplasms Kidney Diseases Antibodies >6 publications with TFRC and Kidney Diseases Organs/Tissues associated with anti-TFRC antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >45 publications with TFRC and Blood Liver Antibodies >28 publications with TFRC and Liver Brain Antibodies >25 publications with TFRC and Brain Lung Antibodies >14 publications with TFRC and Lung Intestine Antibodies >13 publications with TFRC and Intestine Bone Antibodies >12 publications with TFRC and Bone Kidney Antibodies >10 publications with TFRC and Kidney Skin Antibodies >8 publications with TFRC and Skin Embryonic Tissue Antibodies >6 publications with TFRC and Embryonic Tissue Heart Antibodies >6 publications with TFRC and Heart TOP © 2006-24 MyBioSource.com. 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