View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Mouse anti-Human b-Amyloid Monoclonal Antibody Catalog # MBS603379 Unit / Price 0.1 mg / $830 +1 FREE 8GB USB 5x0.1 mg / $3,550 +4 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name b-Amyloid, Monoclonal Antibody Popular Item Full Product Name b-Amyloid (1-40), CT Product Synonym Names Anti -b-Amyloid (1-40), CT Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgG1 Clone Number 6D3 Host Mouse Species Reactivity Human Specificity Recognizes the C-terminus of human beta-amyloid (aa 1-40 isoform). Does not cross-react with beta-amyloid (aa 1-42 isoform). Purity/Purification PurifiedPurified by subsequent thiophilic adsorption and seize exclusion chromatgraphy. Form/Format Supplied as a lyophilized powder from PBS, 0.09% sodium azide. PEG, sucrose. Reconstitute with 1 ml sterile ddH2O. Concentration 0.1 mg/mL (after reconstitution) (lot specific) Immunogen C-terminal peptide of human beta-amyloid (KLH coupled). Preparation and Storage Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Other Notes Small volumes of anti-b-Amyloid antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-b-Amyloid antibody The beta-amyloid peptide (beta A4), proteolytically released from the amyloid precursor protein (APP), is the principal component of senile plaques in Alzheimer's disease. Cleavage of APP by alpha-secretase or alternatively by beta-secretase leads to generation and extracellular release of soluble APP peptides, S-APP-alpha and S-APP-beta, respectively, and the retention of corresponding membrane-anchored C-terminal fragments, C83 and C99. Subsequent processing of C83 by gamma-secretase yields P3 peptides. This is the major secretory pathway and is nonamyloidogenic. Alternatively, presenilin/nicastrin-mediated gamma-secretase processing of C99 releases the amyloid beta proteins, amyloid-beta 40 (Abeta40) and amyloid-beta 42 (Abeta42), major components of amyloid plaques, and the cytotoxic C-terminal fragments, gamma-CTF(50), gamma-CTF(57) and gamma-CTF(59). Product Categories/Family for anti-b-Amyloid antibody Antibodies; Abs to Amyloid Applications Tested/Suitable for anti-b-Amyloid antibody ELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC) Application Notes for anti-b-Amyloid antibody ELISA: 0.1ug/ml.Western Blot: 1ug/ml for for HRPO/ECL detection.Optimal dilutions to be determined by the researcher.Recommended blocking buffer: Casein/Tween-20 based blocking and blot incubation buffer Immunocytochemistry: 1-10ug/ml TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP