View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Mouse anti-Human c-erbB2 Monoclonal Antibody Catalog # MBS600260 Unit / Price 0.5 mL / $715 +1 FREE 8GB USB 5x0.5 mL / $3,055 +3 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name c-erbB2, Monoclonal Antibody Full Product Name c-erbB2 (HER-2, neu Receptor) Product Synonym Names Anti -c-erbB2 (HER-2, neu Receptor) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgG1 Clone Number 3F32 Host Mouse Species Reactivity Human Specificity Recognizes human c-erbB2. Reacts with the intact cells, shows no effect on internalization of c-erbB-2, strongly stimulates (>10-fold) the tyrosine kinase activity and promotes (~40%) the tumorigenic growth in CD1/nude mice of N87 human gastric carcinoma cell line overexpressing c-erbB-2. Does not react with mouse and rat. Purity/Purification Affinity PurifiedPurified by Protein G affinity chromatography. Form/Format Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See C0026-11MX Immunogen Intact SKBR-3 breast cancer cells. Cellular Localization: Cell membrane. MW of Antigen: 185kD. Epitope: Extracellular domain Positive Control SKBR-3 cells. Preparation and Storage May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Other Notes Small volumes of anti-c-erbB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-c-erbB2 antibody c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein Product Categories/Family for anti-c-erbB2 antibody Antibodies; Abs to Oncoproteins Applications Tested/Suitable for anti-c-erbB2 antibody Immunoprecipitation (IP) Application Notes for anti-c-erbB2 antibody Suitable for use in Immuoprecipitation.Dilution: Immunoprecipitation (Native and denatured): 2ug/mg protein lysate. Use Protein G.. TOP NCBI/Uniprot data below describe general gene information for c-erbB2. It may not necessarily be applicable to this product. NCBI GI # 37926854 TOP NCBI Official Full Name Chain P, Single Chain Fv Of C219 Heavy Chain V101l Mutant In Complex With Synthetic Epitope Peptide TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP