NP_001189162.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,754 Da
NCBI Official Full Name
nuclear receptor subfamily 4 group A member 1 isoform 2
NCBI Official Synonym Full Names
nuclear receptor subfamily 4 group A member 1
NCBI Official Synonym Symbols
HMR; N10; TR3; NP10; GFRP1; NAK-1; NGFIB; NUR77 [Similar Products]
NCBI Protein Information
nuclear receptor subfamily 4 group A member 1
UniProt Protein Name
Nuclear receptor subfamily 4 group A member 1
UniProt Synonym Protein Names
Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3
UniProt Synonym Gene Names
NCBI Summary for NR4A1
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
UniProt Comments for NR4A1
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.
Product References and Citations for anti-NR4A1 antibody
Nakai A., Mol. Endocrinol. 4:1438-1443(1990). Chang C., J. Steroid Biochem. 34:391-395(1989). Bondy G.P., Cell Growth Differ. 2:203-208(1991).
Research Articles on NR4A1
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Products associated with anti-NR4A1 antibody
Pathways associated with anti-NR4A1 antibody
Diseases associated with anti-NR4A1 antibody
Organs/Tissues associated with anti-NR4A1 antibody
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