NP_689914.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
258,321 Da
NCBI Official Full Name
ATP-binding cassette sub-family A member 13
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family A (ABC1), member 13
NCBI Protein Information
ATP-binding cassette sub-family A member 13; ATP binding cassette transporter A13; ATP-binding cassette sub-family A member 13 variant 2; ATP-binding cassette sub-family A member 13 variant 3
UniProt Protein Name
ATP-binding cassette sub-family A member 13
UniProt Entry Name
ABCAD_HUMAN
NCBI Summary for ABCA13
In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]
UniProt Comments for ABCA13
ABCA13: In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7p12.3
Cellular Component: integral to membrane
Molecular Function: transporter activity; ATPase activity; ATP binding
Biological Process: metabolic process; transport
Research Articles on ABCA13
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Pathways associated with anti-ABCA13 antibody
Diseases associated with anti-ABCA13 antibody
Organs/Tissues associated with anti-ABCA13 antibody
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