NP_001157465.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
89,832 Da
NCBI Official Full Name
ATP-binding cassette sub-family B member 5 isoform 4
NCBI Official Synonym Full Names
ATP binding cassette subfamily B member 5
NCBI Official Synonym Symbols
ABCB5beta; EST422562; ABCB5alpha [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family B member 5
UniProt Protein Name
ATP-binding cassette sub-family B member 5
UniProt Synonym Protein Names
ABCB5 P-gp; P-glycoprotein ABCB5
NCBI Summary for ABCB5
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
UniProt Comments for ABCB5
Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
Product References and Citations for anti-ABCB5 antibody
(1) Frank, N.Y. and Frank, M.H. ABCB5 gene amplification in human leukemia cells. Leuk. Res. 33 (10), 1303-1305 (2009).
Research Articles on ABCB5
Precautions
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Disclaimer
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Pathways associated with anti-ABCB5 antibody
Diseases associated with anti-ABCB5 antibody
Organs/Tissues associated with anti-ABCB5 antibody
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