ADD16470.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Adrb2
NCBI Official Synonym Full Names
adrenoceptor beta 2, surface
NCBI Protein Information
beta-2 adrenergic receptor; beta-2 adrenoceptor; beta-2 adrenoreceptor; adrenergic receptor, beta 2; Adrenergic beta 2- receptor surface; adrenergic, beta-2-, receptor, surface
UniProt Protein Name
Beta-2 adrenergic receptor
UniProt Synonym Protein Names
Beta-2 adrenoreceptor
UniProt Synonym Gene Names
UniProt Entry Name
ADRB2_RAT
NCBI Summary for Adrb2
binds adrenergic receptor agonist zinterol; plays a role in G-protein coupled receptor regulation of calcium channel current [RGD, Feb 2006]
UniProt Comments for Adrb2
ADRB2: Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: intracellular membrane-bound organelle; integral to plasma membrane; dendrite; integral to membrane; dendritic spine; caveola; membrane; axon; apical plasma membrane; cytoplasm; plasma membrane; nucleus; endosome; receptor complex; sarcolemma
Molecular Function: protein homodimerization activity; G-protein alpha-subunit binding; norepinephrine binding; drug binding; epinephrine binding; PDZ domain binding; ionotropic glutamate receptor binding; protein binding; potassium channel regulator activity; enzyme binding; protein complex binding; dopamine binding; beta2-adrenergic receptor activity; B2 bradykinin receptor binding; adenylate cyclase binding
Biological Process: diet induced thermogenesis; wound healing; regulation of vasodilation; positive regulation of apoptosis; positive regulation of potassium ion transport; regulation of systemic arterial blood pressure by norepinephrine-epinephrine; female pregnancy; positive regulation of vasodilation; G-protein signaling, adenylate cyclase activating pathway; positive regulation of MAPKKK cascade; diaphragm contraction; negative regulation of smooth muscle contraction; positive regulation of cell proliferation; negative regulation of ossification; associative learning; bone resorption; aging; arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway; regulation of smooth muscle contraction; synaptic transmission, glutamatergic; receptor-mediated endocytosis; negative regulation of multicellular organism growth; adenylate cyclase activation; regulation of calcium ion transport; response to testosterone stimulus; regulation of sodium ion transport; liver development; positive regulation of bone mineralization; G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; positive regulation of the force of heart contraction by epinephrine; positive regulation of ATPase activity; positive regulation of protein ubiquitination; response to estrogen stimulus; heat generation; negative regulation of inflammatory response; response to hypoxia; brown fat cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of sensory perception of pain; response to cold; regulation of excitatory postsynaptic membrane potential; positive regulation of skeletal muscle growth; response to progesterone stimulus; positive regulation of heart contraction; norepinephrine-epinephrine vasodilation involved in regulation of systemic arterial blood pressure
Research Articles on Adrb2
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Pathways associated with anti-Adrb2 antibody
Organs/Tissues associated with anti-Adrb2 antibody
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