NP_001131.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
arachidonate 15-lipoxygenase
NCBI Official Synonym Full Names
arachidonate 15-lipoxygenase
NCBI Protein Information
arachidonate 15-lipoxygenase; 15-LOX; 15-lipooxygenase-1; OTTHUMP00000115936; arachidonate omega-6 lipoxygenase
UniProt Protein Name
Arachidonate 15-lipoxygenase
UniProt Synonym Protein Names
Arachidonate omega-6 lipoxygenase
UniProt Synonym Gene Names
UniProt Entry Name
LOX15_HUMAN
UniProt Comments for ALOX15
ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.
Protein type: Motility/polarity/chemotaxis; Lipid Metabolism - linoleic acid; Oxidoreductase; Lipid Metabolism - arachidonic acid; EC 1.13.11.33; EC 1.13.11.31
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: extrinsic to internal side of plasma membrane; membrane; plasma membrane; lipid particle; cytosol
Molecular Function: hepoxilin A3 synthase activity; phosphatidylinositol-4,5-bisphosphate binding; protein binding; arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding
Biological Process: ossification; positive regulation of heterotypic cell-cell adhesion; wound healing; phosphatidylethanolamine biosynthetic process; leukotriene metabolic process; bone mineralization; positive regulation of actin filament polymerization; lipoxygenase pathway; negative regulation of adaptive immune response; arachidonic acid metabolic process; hepoxilin biosynthetic process; inflammatory response; apoptotic cell clearance
Research Articles on ALOX15
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Pathways associated with anti-ALOX15 antibody
Diseases associated with anti-ALOX15 antibody
Organs/Tissues associated with anti-ALOX15 antibody
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