NP_060658.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,948 Da
NCBI Official Full Name
ATPase family AAA domain-containing protein 3A isoform 1
NCBI Official Synonym Full Names
ATPase family, AAA domain containing 3A
NCBI Protein Information
ATPase family AAA domain-containing protein 3A
UniProt Protein Name
ATPase family AAA domain-containing protein 3A
UniProt Entry Name
ATD3A_HUMAN
NCBI Summary for ATAD3A
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008]
UniProt Comments for ATAD3A
ATAD3A: Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone- dependent steroidogenesis. Belongs to the AAA ATPase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane
Molecular Function: ATP binding
Biological Process: cell growth; negative regulation of apoptosis
Research Articles on ATAD3A
Precautions
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Diseases associated with anti-ATAD3A antibody
Organs/Tissues associated with anti-ATAD3A antibody
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