P32261
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UniProt Related Accession #
NCBI Official Full Name
antithrombin III
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
NCBI Protein Information
antithrombin-III; serpin C1; anti-thrombin 3; serpin peptidase inhibitor, clade C, member 1; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
UniProt Protein Name
Antithrombin-III
UniProt Synonym Protein Names
Serpin C1
UniProt Synonym Gene Names
UniProt Entry Name
ANT3_MOUSE
UniProt Comments for Serpinc1
Function: Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
Subcellular location: Secreted › extracellular space.
Tissue specificity: Plasma.
Post-translational modification: Phosphorylation sites are present in the extracelllular medium
Sequence similarities: Belongs to the serpin family.
Product References and Citations for anti-Serpinc1 antibody
1. Damus PS, Rosenberg RD; Antithrombin - Heparin Cofactor; Methods in Enzymology 45, pp 653-669, 1976. 2. Harpel PC; Blood Proteolytic Enzyme Inhibitors: Their Role in Modulating Blood Coagulation and Fibrinolytic Enzyme Pathways; in Hemostasis and Thrombosis, eds. RW Colman, J Hirsh, VJ Marder and EW Salzman, pp. 738- 747, J.B. Lippincott Co., Philadelphia PA, USA, 1982. 3. Griffith MJ, Noyes CM, Church FC; Reactive Site Peptide Structural Similarity between Heparin Cofactor II and Antithrombin III; JBC:260, pp 2218-2225, 1985.
Research Articles on Serpinc1
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Pathways associated with anti-Serpinc1 antibody
Diseases associated with anti-Serpinc1 antibody
Organs/Tissues associated with anti-Serpinc1 antibody
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