NP_031794.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
C-reactive protein
NCBI Official Synonym Full Names
C-reactive protein, pentraxin-related
NCBI Official Synonym Symbols
NCBI Protein Information
C-reactive protein
UniProt Protein Name
C-reactive protein
UniProt Synonym Gene Names
UniProt Comments for CRP
CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1 H3|1 80.13 cM
Cellular Component: extracellular region; extracellular space; filopodium; growth cone
Molecular Function: calcium ion binding; cholesterol binding; complement component C1q binding; low-density lipoprotein particle binding; low-density lipoprotein receptor binding; metal ion binding; protein homodimerization activity
Biological Process: acute-phase response; complement activation, classical pathway; negative regulation of superoxide release; positive regulation of nitric oxide biosynthetic process; positive regulation of superoxide anion generation; protein polymerization; wound healing
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Products associated with anti-CRP antibody
Pathways associated with anti-CRP antibody
Diseases associated with anti-CRP antibody
Organs/Tissues associated with anti-CRP antibody
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