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Add To Compare List anti-C4A antibody :: Rabbit anti-Human C4 Polyclonal Antibody Catalog # MBS273861 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name C4 (C4A), Polyclonal Antibody Popular Item Full Product Name C4 antibody [N1N2-2], N-term Product Synonym Names complement component 4A (Rodgers blood group); C4 antibody; C4A2 antibody; C4A3 antibody; C4A4 antibody; C4A6 antibody; C4S antibody; CO4 antibody; CPAMD2 antibody; MGC164979 antibody; RG antibody; C4A antibody; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody; C4A anaphylatoxin antibody; acidic C4 antibody; acidic complement C4 antibody; Rodgers form of C4 antibody; complement C4-A antibody; complement component 4A (Rodgers blood group) antibody Product Gene Name anti-C4A antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 120790 3D Structure ModBase 3D Structure for B0QZR6 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human Purity/Purification Purified by antigen-affinity chromatography. Form/Format Liquid Concentration 0.52 mg/ml (lot specific) Cellular Localization Secreted Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Predicted Target Size 193 kDa Positive Controls HepG2 Immunogen Recombinant fragment corresponding to a region within amino acids 23 and 302 of C4 (Uniprot ID#P0C0L4) Antigen Species Human Research Area Disease Related; Cardiovascular; Blood; Blood antigens; Disease Related; Cardiovascular; Vessels; Immunology; Innate immune response; Immunology; Innate Immunity; Complement Preparation and Storage Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles. Other Notes Small volumes of anti-C4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-C4A antibody Background: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. [provided by RefSeq]Product Description: Rabbit Polyclonal antibody to C4 (complement component 4A (Rodgers blood group)) Applications Tested/Suitable for anti-C4A antibody Immunohistochemistry (IHC) Paraffin, Western Blot (WB) Application Notes for anti-C4A antibody IHC (Formalin-fixed paraffin-embedded sections): 1:100-1:1000Western blot: 1:500-1:3000Optimal dilutions/concentrations should be determined by the researcher. Western Blot (WB) of anti-C4A antibody Sample (30 ug of whole cell lysate) A: HepG2 5% SDS PAGE diluted at 1:500 Immunohistochemistry (IHC) of anti-C4A antibody Immunohistochemical analysis of paraffin-embedded Hepatoma, using C4 antibody [N1N2-2], N-term antibody at 1:200 dilution. TOP NCBI/Uniprot data below describe general gene information for C4A. It may not necessarily be applicable to this product. NCBI GI # 356582273 NCBI GeneID 720 NCBI Accession # NP_001239133 [Other Products] NCBI GenBank Nucleotide # NM_007293 [Other Products] UniProt Primary Accession # B0QZR6 [Other Products] UniProt Secondary Accession # P01028; P78445; Q13160; Q13906; A6H8M8; A6NHJ5; A7E2V2; B0QZR6; B0V2C8; B2RUT6; B7ZVZ6[Other Products] UniProt Related Accession # P0C0L4[Other Products] Molecular Weight 187,704 Da TOP NCBI Official Full Name complement C4-A isoform 2 preproprotein NCBI Official Synonym Full Names complement component 4A (Rodgers blood group) NCBI Official Symbol C4A [Similar Products] NCBI Official Synonym Symbols C4; RG; C4S; CO4; C4A2; C4A3; C4A4; C4A6; C4AD; CPAMD2 [Similar Products] NCBI Protein Information complement C4-A; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C4A anaphylatoxin; Rodgers form of C4; acidic C4; acidic complement C4 UniProt Protein Name Complement C4-A UniProt Synonym Protein Names Acidic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2Cleaved into the following 6 chains:Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain Protein Family Complement C4 UniProt Gene Name C4A [Similar Products] UniProt Synonym Gene Names CO4; CPAMD2 [Similar Products] UniProt Entry Name CO4A_HUMAN TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-C4A antibody Reference Product PubMed Publications C1S antibody >28 publications with C4A and C1S TNXA antibody >13 publications with C4A and TNXA CYP21A2 antibody >8 publications with C4A and CYP21A2 C8A antibody >4 publications with C4A and C8A HLA-ABC antibody >3 publications with C4A and HLA-ABC C5AR1 antibody >2 publications with C4A and C5AR1 Pathways associated with anti-C4A antibody Products by Pathway Pathway Diagram Activation Of C3 And C5 Pathway antibodies Activation Of C3 And C5 Pathway Diagram Allograft Rejection Pathway antibodies Allograft Rejection Pathway Diagram Complement Activation, Classical Pathway antibodies Complement Activation, Classical Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement And Coagulation Cascades Pathway antibodies Complement And Coagulation Cascades Pathway Diagram Complement Cascade Pathway antibodies Complement Cascade Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Initial Triggering Of Complement Pathway antibodies Initial Triggering Of Complement Pathway Diagram Innate Immune System Pathway antibodies Innate Immune System Pathway Diagram Pertussis Pathway antibodies Pertussis Pathway Diagram Diseases associated with anti-C4A antibody Disease Name Pubmed Publications Lupus Erythematosus, Systemic Antibodies >160 publications with C4A and Lupus Erythematosus, Systemic Inflammation Antibodies >92 publications with C4A and Inflammation Kidney Diseases Antibodies >53 publications with C4A and Kidney Diseases Hyperplasia Antibodies >43 publications with C4A and Hyperplasia Urogenital Abnormalities Antibodies >36 publications with C4A and Urogenital Abnormalities Liver Diseases Antibodies >34 publications with C4A and Liver Diseases Necrosis Antibodies >33 publications with C4A and Necrosis Heart Diseases Antibodies >32 publications with C4A and Heart Diseases Hepatitis Antibodies >29 publications with C4A and Hepatitis Immunologic Deficiency Syndromes Antibodies >27 publications with C4A and Immunologic Deficiency Syndromes Organs/Tissues associated with anti-C4A antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >468 publications with C4A and Blood Liver Antibodies >66 publications with C4A and Liver Kidney Antibodies >52 publications with C4A and Kidney Mouth Antibodies >51 publications with C4A and Mouth Heart Antibodies >30 publications with C4A and Heart Lung Antibodies >26 publications with C4A and Lung Eye Antibodies >18 publications with C4A and Eye Muscle Antibodies >18 publications with C4A and Muscle Brain Antibodies >17 publications with C4A and Brain Adrenal Gland Antibodies >11 publications with C4A and Adrenal Gland TOP © 2006-24 MyBioSource.com. 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