AAH11522.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CD164 molecule, sialomucin
NCBI Official Synonym Full Names
CD164 molecule, sialomucin
NCBI Protein Information
sialomucin core protein 24; MGC-24v; CD164 variant C; CD164 antigen, sialomucin; multi-glycosylated core protein 24
UniProt Protein Name
Sialomucin core protein 24
UniProt Synonym Protein Names
Endolyn; Multi-glycosylated core protein 24; MGC-24; MGC-24v; CD_antigen: CD164
UniProt Synonym Gene Names
UniProt Entry Name
MUC24_HUMAN
NCBI Summary for CD164
Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (Watt et al., 1998 [PubMed 9680353]; Forde et al., 2007 [PubMed 17077324]).[supplied by OMIM, Aug 2008]
UniProt Comments for CD164
CD164: Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes. Belongs to the CD164 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 6q21
Cellular Component: integral to plasma membrane; lysosomal membrane; lysosome; extracellular region; plasma membrane; endosome membrane; endosome
Molecular Function: protein binding
Biological Process: heterophilic cell adhesion; negative regulation of cell proliferation; muscle development; multicellular organismal development; immune response; hemopoiesis; negative regulation of cell adhesion; cell adhesion; signal transduction
Research Articles on CD164
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Products associated with anti-CD164 antibody
Pathways associated with anti-CD164 antibody
Diseases associated with anti-CD164 antibody
Organs/Tissues associated with anti-CD164 antibody
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