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Add To Compare List anti-NT5E antibody :: Rabbit CD73 Polyclonal Antibody Catalog # MBS270813 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name CD73 (NT5E), Polyclonal Antibody Full Product Name CD73 antibody [N1N3] Product Synonym Names 5'-nucleotidase; ecto (CD73); CD73 antibody; E5NT antibody; NT antibody; NT5 antibody; NTE antibody; eN antibody; eNT antibody; NT5E antibody; 5'-NT antibody; Purine 5-Prime-Nucleotidase antibody; 5'-nucleotidase antibody; ecto-5'-nucleotidase antibody; "5'-nucleotidase; ecto (CD73) antibody" Product Gene Name anti-NT5E antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 129190 3D Structure ModBase 3D Structure for P21589 Clonality Polyclonal Host Rabbit Species Reactivity HumanPredicted Reactivity: Mouse (90%), Rat (91%), Bovine (93%) Purity/Purification Purified by antigen-affinity chromatography. Form/Format Liquid Concentration 0.78 mg/ml (lot specific) Cellular Localization Cell membrane, GPI-anchor Storage Buffer 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Predicted Target Size 63 kDa Positive Controls HepG2, HCT116 Immunogen Recombinant fragment corresponding to a region within amino acids 35 and 261 of CD73 (Uniprot ID#P21589) Antigen Species Human Research Area Immunology; CD marker; Metabolism; DNA metabolism Preparation and Storage Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles. Other Notes Small volumes of anti-NT5E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-NT5E antibody Background: Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.[supplied by OMIM]Product Description: Rabbit Polyclonal antibody to CD73 (5'-nucleotidase, ecto (CD73)) Applications Tested/Suitable for anti-NT5E antibody Immunohistochemistry (IHC) Paraffin, Western Blot (WB) Application Notes for anti-NT5E antibody IHC (Formalin-fixed paraffin-embedded sections): 1:100-1:1000Western blot: 1:500-1:3000IHC (Formalin-fixed paraffin-embedded sections): suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)Optimal dilutions/concentrations should be determined by the researcher. Western Blot (WB) of anti-NT5E antibody Sample (30 ug of whole cell lysate) A: HepG2 B: HCT116 12% SDS PAGE diluted at 1:1000 Immunohistochemistry (IHC) of anti-NT5E antibody Immunohistochemical analysis of paraffin-embedded J5 xenograft, using CD73 antibody at 1:250 dilution. TOP NCBI/Uniprot data below describe general gene information for NT5E. It may not necessarily be applicable to this product. NCBI GI # 325651886 NCBI GeneID 4907 NCBI Accession # NP_001191742 [Other Products] NCBI GenBank Nucleotide # NM_001204813 [Other Products] UniProt Primary Accession # P21589 [Other Products] UniProt Secondary Accession # O75520; Q5W116; B3KQI8[Other Products] UniProt Related Accession # P21589[Other Products] Molecular Weight 57,949 Da TOP NCBI Official Full Name 5'-nucleotidase isoform 2 preproprotein NCBI Official Synonym Full Names 5'-nucleotidase, ecto (CD73) NCBI Official Symbol NT5E [Similar Products] NCBI Official Synonym Symbols NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA [Similar Products] NCBI Protein Information 5'-nucleotidase; 5'-NT; Purine 5-Prime-Nucleotidase; ecto-5'-nucleotidase UniProt Protein Name 5'-nucleotidase UniProt Synonym Protein Names Ecto-5'-nucleotidase; CD_antigen: CD73 UniProt Gene Name NT5E [Similar Products] UniProt Synonym Gene Names NT5; NTE; 5'-NT [Similar Products] UniProt Entry Name 5NTD_HUMAN TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-NT5E antibody Reference Product PubMed Publications ENPP1 antibody >5 publications with NT5E and ENPP1 ADA antibody >3 publications with NT5E and ADA ENTPD1 antibody >3 publications with NT5E and ENTPD1 Pathways associated with anti-NT5E antibody Products by Pathway Pathway Diagram HIF-1-alpha Transcription Factor Network Pathway antibodies HIF-1-alpha Transcription Factor Network Pathway Diagram Metabolic Pathways antibodies Metabolic Pathways Diagram Metabolism Pathway antibodies Metabolism Pathway Diagram Metabolism Of Nucleotides Pathway antibodies Metabolism Of Nucleotides Pathway Diagram Nicotinate And Nicotinamide Metabolism Pathway antibodies Nicotinate And Nicotinamide Metabolism Pathway Diagram Nicotinate And Nicotinamide Metabolism Pathway antibodies Nicotinate And Nicotinamide Metabolism Pathway Diagram Purine Catabolism Pathway antibodies Purine Catabolism Pathway Diagram Purine Metabolism Pathway antibodies Purine Metabolism Pathway Diagram Purine Metabolism Pathway antibodies Purine Metabolism Pathway Diagram Purine Metabolism Pathway antibodies Purine Metabolism Pathway Diagram Diseases associated with anti-NT5E antibody Disease Name Pubmed Publications Inflammation Antibodies >17 publications with NT5E and Inflammation Necrosis Antibodies >9 publications with NT5E and Necrosis Breast Neoplasms Antibodies >9 publications with NT5E and Breast Neoplasms Nervous System Diseases Antibodies >9 publications with NT5E and Nervous System Diseases Disease Models, Animal Antibodies >8 publications with NT5E and Disease Models, Animal Pain Antibodies >7 publications with NT5E and Pain Brain Diseases Antibodies >5 publications with NT5E and Brain Diseases Kidney Diseases Antibodies >4 publications with NT5E and Kidney Diseases Heart Diseases Antibodies >4 publications with NT5E and Heart Diseases Acute Kidney Injury Antibodies >3 publications with NT5E and Acute Kidney Injury Organs/Tissues associated with anti-NT5E antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >34 publications with NT5E and Blood Vascular Antibodies >20 publications with NT5E and Vascular Bone Antibodies >14 publications with NT5E and Bone Bone Marrow Antibodies >9 publications with NT5E and Bone Marrow Brain Antibodies >9 publications with NT5E and Brain Muscle Antibodies >8 publications with NT5E and Muscle Mouth Antibodies >8 publications with NT5E and Mouth Kidney Antibodies >6 publications with NT5E and Kidney Ganglia Antibodies >6 publications with NT5E and Ganglia Embryonic Tissue Antibodies >5 publications with NT5E and Embryonic Tissue TOP © 2006-24 MyBioSource.com. 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