View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-DAPK2 antibody :: Rabbit DAPK2 Polyclonal Antibody Catalog # MBS300408 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name DAPK2, Polyclonal Antibody Full Product Name Rabbit Anti-Human DAPK2 Polyclonal Antibody Product Gene Name anti-DAPK2 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity HumanPredicted Reactivity: Bovine, Mouse, Rabbit, Rat Form/Format 1.0 ml immunogen affinity purified rabbit polyclonal antibody in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide. Immunogen Synthetic peptide corresponding to C-terminus of human DAPK2 protein. Control Tissue Breast Carcinoma Cellular Localization Cytoplasm Entrez Gene Code 23604 Pathway Kinase and Phosphatase Preparation and Storage Store at 2-8 degree C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date. There are no definitive signs to indicate instability of this product; therefore, positive and negative controls should be tested simultaneously with unknown specimens. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support. Other Notes Small volumes of anti-DAPK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-DAPK2 antibody Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFN? induced apoptosis. A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1. Ectopicly expressed DAPK2 induced apoptosis in various types of cells. DAPK has high sequence homology to ZIP kinase and DRAK1/2, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. The messenger RNA of DAPK2 is expressed in multiple human tissues. Applications Tested/Suitable for anti-DAPK2 antibody Immunohistochemistry (IHC) Paraffin Application Notes for anti-DAPK2 antibody Immunohistochemistry ProcedureSpecimen Preparation: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:50. The dilutions are estimates; actual results may differ because of variability in methods and protocols. Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Primary Antibody Incubation: Incubate for 30 minutes at room temperature. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Visualization: Detect the antibody as instructed by the instructions provided with the visualization system.Immunohistochemistry Dilution: 1:50IHC Positive Control: Breast Immunohistochemistry (IHC) of anti-DAPK2 antibody Human breast stained with anti-DAPK2 antibody TOP NCBI/Uniprot data below describe general gene information for DAPK2. It may not necessarily be applicable to this product. NCBI GI # 14670383 NCBI GeneID 23604 NCBI Accession # NP_055141.2 [Other Products] NCBI GenBank Nucleotide # NM_014326.3 [Other Products] UniProt Secondary Accession # O75892; Q24JS1; E9JGM7[Other Products] UniProt Related Accession # Q9UIK4[Other Products] Molecular Weight 42 kDa TOP NCBI Official Full Name death-associated protein kinase 2 NCBI Official Synonym Full Names death-associated protein kinase 2 NCBI Official Symbol DAPK2 [Similar Products] NCBI Official Synonym Symbols DRP1; DRP-1 [Similar Products] NCBI Protein Information death-associated protein kinase 2; DAP kinase 2; DAP-kinase-related protein 1 beta isoform UniProt Protein Name Death-associated protein kinase 2 UniProt Synonym Protein Names DAP-kinase-related protein 1; DRP-1 Protein Family Death-associated protein kinase UniProt Gene Name DAPK2 [Similar Products] UniProt Synonym Gene Names DAP kinase 2; DRP-1 [Similar Products] UniProt Entry Name DAPK2_HUMAN TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-DAPK2 antibody Reference Product PubMed Publications DAP antibody >148 publications with DAPK2 and DAP MAPK1 antibody >8 publications with DAPK2 and MAPK1 MAPK3 antibody >7 publications with DAPK2 and MAPK3 CAMK2A antibody >1 publications with DAPK2 and CAMK2A Pathways associated with anti-DAPK2 antibody Products by Pathway Pathway Diagram Bladder Cancer Pathway antibodies Bladder Cancer Pathway Diagram Bladder Cancer Pathway antibodies Bladder Cancer Pathway Diagram Extrinsic Pathway antibodies Extrinsic Pathway Diagram Pathways In Cancer antibodies Pathways In Cancer Diagram Programmed Cell Death Pathway antibodies Programmed Cell Death Pathway Diagram Role Of DCC In Regulating Apoptosis Pathway antibodies Role Of DCC In Regulating Apoptosis Pathway Diagram Diseases associated with anti-DAPK2 antibody Disease Name Pubmed Publications Brain Diseases Antibodies >60 publications with DAPK2 and Brain Diseases Necrosis Antibodies >59 publications with DAPK2 and Necrosis Carcinoma, Squamous Cell Antibodies >52 publications with DAPK2 and Carcinoma, Squamous Cell Neoplasms, Experimental Antibodies >42 publications with DAPK2 and Neoplasms, Experimental Inflammation Antibodies >31 publications with DAPK2 and Inflammation Breast Neoplasms Antibodies >31 publications with DAPK2 and Breast Neoplasms Cell Transformation, Neoplastic Antibodies >25 publications with DAPK2 and Cell Transformation, Neoplastic Disease Models, Animal Antibodies >23 publications with DAPK2 and Disease Models, Animal Heart Diseases Antibodies >12 publications with DAPK2 and Heart Diseases Kidney Diseases Antibodies >11 publications with DAPK2 and Kidney Diseases Organs/Tissues associated with anti-DAPK2 antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >100 publications with DAPK2 and Blood Lung Antibodies >73 publications with DAPK2 and Lung Brain Antibodies >71 publications with DAPK2 and Brain Vascular Antibodies >32 publications with DAPK2 and Vascular Stomach Antibodies >32 publications with DAPK2 and Stomach Lymph Node Antibodies >26 publications with DAPK2 and Lymph Node Bone Marrow Antibodies >20 publications with DAPK2 and Bone Marrow Prostate Antibodies >15 publications with DAPK2 and Prostate Skin Antibodies >11 publications with DAPK2 and Skin Intestine Antibodies >9 publications with DAPK2 and Intestine TOP © 2006-24 MyBioSource.com. 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