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Add To Compare List anti-FLNA antibody :: Rabbit Filamin A Polyclonal Antibody Catalog # MBS270630 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Filamin A (FLNA), Polyclonal Antibody Full Product Name Filamin A antibody [C2], C-term Product Synonym Names filamin A; alpha; ABP-280 antibody; ABPX antibody; CVD1 antibody; DKFZp434P031 antibody; FLN antibody; FLN-A antibody; FLN1 antibody; FMD antibody; MNS antibody; NHBP antibody; OPD antibody; OPD1 antibody; OPD2 antibody; XLVD antibody; XMVD antibody; FLNA antibody; filamin-1 antibody; actin binding protein 280 antibody; alpha-filamin antibody; endothelial actin-binding protein antibody; filamin-A antibody; non-muscle filamin antibody; "filamin A; alpha antibody" Product Gene Name anti-FLNA antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 300017 3D Structure ModBase 3D Structure for P21333 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse, RatPredicted Reactivity: Rabbit (98%) Purity/Purification Purified by antigen-affinity chromatography. Form/Format Liquid Concentration 0.42 mg/ml (lot specific) Cellular Localization Cytoplasm, cell cortex, cytoskeleton Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Predicted Target Size 281 kDa Positive Controls 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse kidney, PC-12, Rat2 Immunogen Recombinant fragment corresponding to a region within amino acids 1769 and 2098 of Filamin A (Uniprot ID#P21333) Antigen Species Human Preparation and Storage Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles. Other Notes Small volumes of anti-FLNA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-FLNA antibody Background: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.Product Description: Rabbit Polyclonal antibody to Filamin A (filamin A, alpha) Applications Tested/Suitable for anti-FLNA antibody Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) Application Notes for anti-FLNA antibody ICC/IF: 1:100-1:1000IHC (Formalin-fixed paraffin-embedded sections): 1:100-1:1000Western blot: 1:500-1:3000Optimal dilutions/concentrations should be determined by the researcher. Western Blot (WB) of anti-FLNA antibody Sample (50 ug of whole cell lysate) A: mouse kidney 5% SDS PAGE diluted at 1:1000 Western Blot (WB) of anti-FLNA antibody Sample (30 ug of whole cell lysate) A: H1299 B: Hep G2 5% SDS PAGE Diluted at 1:1000 Western Blot (WB) of anti-FLNA antibody Filamin A antibody detects Filamin A protein by western blot analysis.A. 30 ug PC-12 whole cell lysate/extract B. 30 ug Rat2 whole cell lysate/extract5 % SDS-PAGEFilamin A antibody dilution: 1:1000 Immunohistochemistry (IHC) of anti-FLNA antibody Filamin A antibody [C2], C-term detects Filamin A protein at cytosol on mouse esophagus by immunohistochemical analysis. Sample: Paraffin-embedded mouse esophagus. Filamin A antibody [C2], C-term dilution: 1:500. Immunocytochemistry/Immunofluorescence (ICC/IF) of anti-FLNA antibody Immunofluorescence analysis of methanol-fixed HeLa, using Filamin A alpha 2 antibody at 1:200 dilution. TOP NCBI/Uniprot data below describe general gene information for FLNA. It may not necessarily be applicable to this product. NCBI GI # 160420317 NCBI GeneID 2316 NCBI Accession # NP_001104026 [Other Products] NCBI GenBank Nucleotide # NM_001110556 [Other Products] UniProt Primary Accession # P21333 [Other Products] UniProt Secondary Accession # Q5HY53; Q5HY55; Q8NF52; E9KL45[Other Products] UniProt Related Accession # P21333[Other Products] Molecular Weight 280,018 Da TOP NCBI Official Full Name filamin-A isoform 2 NCBI Official Synonym Full Names filamin A, alpha NCBI Official Symbol FLNA [Similar Products] NCBI Official Synonym Symbols FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280 [Similar Products] NCBI Protein Information filamin-A; actin binding protein 280; alpha-filamin; endothelial actin-binding protein; filamin-1; non-muscle filamin UniProt Protein Name Filamin-A UniProt Synonym Protein Names Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin Protein Family Filamin UniProt Gene Name FLNA [Similar Products] UniProt Synonym Gene Names FLN; FLN1; FLN-A; ABP-280 [Similar Products] UniProt Entry Name FLNA_HUMAN TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-FLNA antibody Reference Product PubMed Publications RAC1 antibody >8 publications with FLNA and RAC1 CDC42 antibody >6 publications with FLNA and CDC42 ARHGAP24 antibody >6 publications with FLNA and ARHGAP24 FBLIM1 antibody >3 publications with FLNA and FBLIM1 TTN antibody >1 publications with FLNA and TTN ITGB1 antibody >1 publications with FLNA and ITGB1 Pathways associated with anti-FLNA antibody Products by Pathway Pathway Diagram Androgen Receptor Signaling Pathway antibodies Androgen Receptor Signaling Pathway Diagram Cell Junction Organization Pathway antibodies Cell Junction Organization Pathway Diagram Cell-Cell Communication Pathway antibodies Cell-Cell Communication Pathway Diagram Cell-extracellular Matrix Interactions Pathway antibodies Cell-extracellular Matrix Interactions Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram GP1b-IX-V Activation Signalling Pathway antibodies GP1b-IX-V Activation Signalling Pathway Diagram Hemostasis Pathway antibodies Hemostasis Pathway Diagram MAPK Signaling Pathway antibodies MAPK Signaling Pathway Diagram Diseases associated with anti-FLNA antibody Disease Name Pubmed Publications Nervous System Diseases Antibodies >75 publications with FLNA and Nervous System Diseases Periventricular Nodular Heterotopia Antibodies >61 publications with FLNA and Periventricular Nodular Heterotopia HETEROTOPIA, PERIVENTRICULAR, X-LINKED DOMINANT Antibodies >61 publications with FLNA and HETEROTOPIA, PERIVENTRICULAR, X-LINKED DOMINANT Brain Diseases Antibodies >38 publications with FLNA and Brain Diseases Epilepsy Antibodies >35 publications with FLNA and Epilepsy Frontometaphyseal dysplasia Antibodies >12 publications with FLNA and Frontometaphyseal dysplasia Heart Diseases Antibodies >10 publications with FLNA and Heart Diseases Prostatic Diseases Antibodies >9 publications with FLNA and Prostatic Diseases Osteochondrodysplasias Antibodies >8 publications with FLNA and Osteochondrodysplasias TERMINAL OSSEOUS DYSPLASIA Antibodies >5 publications with FLNA and TERMINAL OSSEOUS DYSPLASIA Organs/Tissues associated with anti-FLNA antibody Organ/Tissue Name Pubmed Publications Brain Antibodies >76 publications with FLNA and Brain Blood Antibodies >31 publications with FLNA and Blood Vascular Antibodies >24 publications with FLNA and Vascular Bone Antibodies >21 publications with FLNA and Bone Heart Antibodies >19 publications with FLNA and Heart Muscle Antibodies >18 publications with FLNA and Muscle Skin Antibodies >13 publications with FLNA and Skin Prostate Antibodies >12 publications with FLNA and Prostate Nerve Antibodies >11 publications with FLNA and Nerve Lung Antibodies >10 publications with FLNA and Lung TOP © 2006-24 MyBioSource.com. 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