NP_059106.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35,379 Da
NCBI Official Full Name
homeobox protein Hox-C13
NCBI Official Synonym Full Names
homeobox C13
NCBI Protein Information
homeobox protein Hox-C13
UniProt Protein Name
Homeobox protein Hox-C13
UniProt Synonym Protein Names
Homeobox protein Hox-3G
UniProt Synonym Gene Names
UniProt Entry Name
HXC13_HUMAN
NCBI Summary for HOXC13
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla. [provided by RefSeq, Jul 2008]
UniProt Comments for HOXC13
HOXC13: Transcription factor which plays a role in hair follicle differentiation. Regulates FOXQ1 expression and that of other hair-specific genes. Belongs to the Abd-B homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 12q13.3
Cellular Component: nucleus
Molecular Function: protein binding; sequence-specific DNA binding; chromatin binding
Biological Process: anterior/posterior pattern formation; tongue morphogenesis; anatomical structure morphogenesis; transcription, DNA-dependent; hair follicle development; positive regulation of transcription from RNA polymerase II promoter
Disease: Ectodermal Dysplasia 9, Hair/nail Type
Research Articles on HOXC13
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Products associated with anti-HOXC13 antibody
Diseases associated with anti-HOXC13 antibody
Organs/Tissues associated with anti-HOXC13 antibody
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