NP_795352.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
125,231 Da
NCBI Official Full Name
inaD-like protein
NCBI Official Synonym Full Names
PATJ, crumbs cell polarity complex component
NCBI Protein Information
inaD-like protein
UniProt Protein Name
InaD-like protein
UniProt Synonym Protein Names
Pals1-associated tight junction protein; Protein associated to tight junctions
UniProt Synonym Gene Names
UniProt Entry Name
INADL_HUMAN
NCBI Summary for INADL
This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008]
UniProt Comments for INADL
INADL: Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 1p31.3
Cellular Component: apical plasma membrane; perinuclear region of cytoplasm; plasma membrane; protein complex; tight junction
Molecular Function: protein binding
Research Articles on INADL
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Products associated with anti-INADL antibody
Pathways associated with anti-INADL antibody
Diseases associated with anti-INADL antibody
Organs/Tissues associated with anti-INADL antibody
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