NP_036458.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,380 Da
NCBI Official Full Name
microtubule-associated protein RP/EB family member 3
NCBI Official Synonym Full Names
microtubule associated protein RP/EB family member 3
NCBI Protein Information
microtubule-associated protein RP/EB family member 3
UniProt Protein Name
Microtubule-associated protein RP/EB family member 3
UniProt Synonym Protein Names
EB1 protein family member 3; EBF3; End-binding protein 3; EB3; RP3
UniProt Synonym Gene Names
UniProt Entry Name
MARE3_HUMAN
NCBI Summary for MAPRE3
The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]
UniProt Comments for MAPRE3
EB3: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. Belongs to the MAPRE family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Microtubule-binding
Chromosomal Location of Human Ortholog: 2p23.3-p23.1
Cellular Component: cytoplasm; cytoplasmic microtubule; microtubule cytoskeleton; midbody; perinuclear region of cytoplasm
Molecular Function: microtubule binding; protein binding
Biological Process: cell division; mitosis; positive regulation of cyclin-dependent protein kinase activity; positive regulation of transcription, DNA-dependent
Research Articles on MAPRE3
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Products associated with anti-MAPRE3 antibody
Diseases associated with anti-MAPRE3 antibody
Organs/Tissues associated with anti-MAPRE3 antibody
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