NP_001126748.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
neprilysin
NCBI Protein Information
neprilysin
UniProt Protein Name
Neprilysin
UniProt Synonym Protein Names
Atriopeptidase; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD_antigen: CD10
UniProt Synonym Gene Names
UniProt Entry Name
NEP_PONAB
UniProt Comments for MME
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
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Products associated with anti-MME antibody
Pathways associated with anti-MME antibody
Diseases associated with anti-MME antibody
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