View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-OCLN antibody :: Guinea pig Occludin Polyclonal Antibody Catalog # MBS584484 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Occludin (OCLN), Polyclonal Antibody Popular Item Full Product Name Polyclonal antibody to human occludin Product Gene Name anti-OCLN antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Polyclonal Isotype Guinea pig Ig Host Guinea pig Species Reactivity Reactivity: Human. Cross reactivity: Canine, Mouse, Rat Form/Format 1 ml (100 ug/ml) 0.2 um filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.For unit size 0.5 mg or larger: PBS only (concentration< 0.5mg/ml) Species Guinea pig Ig Other recommended product MBS584478: Polyclonal antibody against Human ZO-1MBS584473: Polyclonal antibody against Human ZO-1 alpha-plusMBS584512: Polyclonal antibody against Human ZO-1 alpha-minusMBS584514: Polyclonal antibody against Human ZO-2MBS584196: Monoclonal antibody against Human JAM-A (JAM-1), clone M.Ab. F11 Preparation and Storage Product should be stored at 4 degree C. Under recommended storage conditions, product is stable for one year. Other Notes Small volumes of anti-OCLN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-OCLN antibody Product Description: The polyclonal antibody reacts with human occludin, an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1). The antibody is generated against recombinant human occludin (aa 358-504). The polyclonal anti-human occludin antibody cross reacts with rat, mouse and dog occludin. Applications Tested/Suitable for anti-OCLN antibody Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot Application Notes for anti-OCLN antibody Application Use: For immunohistology, immunfluorescence and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.. TOP NCBI/Uniprot data below describe general gene information for OCLN. It may not necessarily be applicable to this product. NCBI GI # 50978954 NCBI GeneID 403844 NCBI Accession # NP_001003195.1 [Other Products] NCBI GenBank Nucleotide # NM_001003195.1 [Other Products] UniProt Related Accession # Q28269[Other Products] Molecular Weight 59,275 Da[Similar Products] TOP NCBI Official Full Name occludin NCBI Official Symbol OCLN [Similar Products] NCBI Protein Information occludin UniProt Protein Name Occludin Protein Family Occludin UniProt Gene Name OCLN [Similar Products] UniProt Entry Name OCLN_CANFA TOP TOP UniProt Comments for OCLN May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Interacts with ZO-1. Product References and Citations for anti-OCLN antibody Van Itallie, C et al; Occludin confers adhesiveness when expressed in fibroblasts. J Cell Sci 1997, 110: 1113. Research Articles on OCLN 1. EhCP112 and EhADH112 co-localize with occludin and claudin-1 at tight junctions. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. 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TOP Products associated with anti-OCLN antibody Reference Product PubMed Publications TJP1 antibody >525 publications with OCLN and TJP1 CLDN5 antibody >128 publications with OCLN and CLDN5 CLDN4 antibody >63 publications with OCLN and CLDN4 TJP2 antibody >48 publications with OCLN and TJP2 CLDN3 antibody >47 publications with OCLN and CLDN3 TJP3 antibody >13 publications with OCLN and TJP3 CLDN11 antibody >11 publications with OCLN and CLDN11 CGN antibody >7 publications with OCLN and CGN YES1 antibody >1 publications with OCLN and YES1 Pathways associated with anti-OCLN antibody Products by Pathway Pathway Diagram Cell Adhesion Molecules (CAMs) Pathway antibodies Cell Adhesion Molecules (CAMs) Pathway Diagram Cell Adhesion Molecules (CAMs) Pathway antibodies Cell Adhesion Molecules (CAMs) Pathway Diagram Hepatitis C Pathway antibodies Hepatitis C Pathway Diagram Hepatitis C Pathway antibodies Hepatitis C Pathway Diagram Leukocyte Transendothelial Migration Pathway antibodies Leukocyte Transendothelial Migration Pathway Diagram Leukocyte Transendothelial Migration Pathway antibodies Leukocyte Transendothelial Migration Pathway Diagram Tight Junction Pathway antibodies Tight Junction Pathway Diagram Tight Junction Pathway antibodies Tight Junction Pathway Diagram Diseases associated with anti-OCLN antibody Disease Name Pubmed Publications Inflammation Antibodies >140 publications with OCLN and Inflammation Disease Models, Animal Antibodies >113 publications with OCLN and Disease Models, Animal Necrosis Antibodies >81 publications with OCLN and Necrosis Cardiovascular Diseases Antibodies >78 publications with OCLN and Cardiovascular Diseases Edema Antibodies >59 publications with OCLN and Edema Liver Diseases Antibodies >42 publications with OCLN and Liver Diseases Retinal Diseases Antibodies >32 publications with OCLN and Retinal Diseases Colitis Antibodies >28 publications with OCLN and Colitis Kidney Diseases Antibodies >15 publications with OCLN and Kidney Diseases Hemorrhage Antibodies >13 publications with OCLN and Hemorrhage TOP © 2006-24 MyBioSource.com. 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