NP_065648.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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Molecular Weight
12,825 Da
NCBI Official Full Name
parathyroid hormone
NCBI Official Synonym Full Names
parathyroid hormone
NCBI Official Synonym Symbols
NCBI Protein Information
parathyroid hormone
UniProt Protein Name
Parathyroid hormone
UniProt Synonym Gene Names
UniProt Entry Name
Q9Z0L6_MOUSE
UniProt Comments for PTH
PTH: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Belongs to the parathyroid hormone family.
Protein type: Hormone; Apoptosis; Secreted; Secreted, signal peptide
Cellular Component: extracellular space; cell; intracellular
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; type 1 parathyroid hormone receptor binding; peptide hormone receptor binding; parathyroid hormone receptor binding; hormone activity
Biological Process: transcription from RNA polymerase II promoter; positive regulation of signal transduction; positive regulation of glycogen biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of bone mineralization; G-protein signaling, adenylate cyclase activating pathway; Rho protein signal transduction; positive regulation of ossification; cellular calcium ion homeostasis; positive regulation of glucose import; cell-cell signaling; regulation of gene expression; positive regulation of cAMP biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; skeletal development; bone resorption
Disease: Hypoparathyroidism, Familial Isolated
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Products associated with anti-PTH antibody
Pathways associated with anti-PTH antibody
Diseases associated with anti-PTH antibody
Organs/Tissues associated with anti-PTH antibody
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