AAX84843.1
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UniProt Secondary Accession #
NCBI Official Full Name
RNA binding motif protein 9
UniProt Protein Name
RNA binding protein fox-1 homolog 2
UniProt Synonym Protein Names
Fox-1 homolog B; Hexaribonucleotide-binding protein 2; RNA-binding motif protein 9; RNA-binding protein 9; Repressor of tamoxifen transcriptional activity
UniProt Synonym Gene Names
UniProt Entry Name
RFOX2_HUMAN
UniProt Comments for RBFOX2
RBM9: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. RNA-binding protein that seems to act as a coregulatory factor of ER-alpha. 10 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor; RNA-binding; RNA splicing
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: mRNA binding; protein binding; RNA binding; nucleotide binding; transcription factor binding; transcription corepressor activity
Biological Process: estrogen receptor signaling pathway; RNA metabolic process; dendrite morphogenesis; radial glia guided migration of Purkinje cell; RNA splicing; mRNA processing; negative regulation of transcription, DNA-dependent; neuromuscular process controlling balance; regulation of alternative nuclear mRNA splicing, via spliceosome; regulation of cell proliferation
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